Malaria, a mosquito‐borne infectious disease caused by parasites of the genus Plasmodium
continues to be a major health problem worldwide. The unicellular Plasmodium‐parasites …

More than a century after the discovery of Plasmodium spp. parasites, the pathogenesis of
severe malaria is still not well understood. The majority of malaria cases are caused by …

Abstract Purpose of Review To discuss the neurological complications and pathophysiology
of organ damage following malaria infection. Recent Findings The principal advancement …

Cytoadhesion of P lasmodium falciparum‐infected erythrocytes to host microvasculature is a
key virulence determinant. Parasite binding is mediated by a large family of clonally variant …

Cerebral malaria is a deadly outcome of infection by Plasmodium falciparum, occurring
when parasite-infected erythrocytes accumulate in the brain. These erythrocytes display …

Cerebral malaria (CM) is a major cause of mortality in African children and the mechanisms
underlying its development, namely how malaria-infected erythrocytes (IEs) cause disease …

Plasmodium falciparum malaria is responsible for nearly one million annual deaths
worldwide. Because of the difficulty in monitoring the pathogenesis of cerebral malaria in …

The past decade has seen an unprecedented surge in political commitment and
international funding for malaria control. Coverage with existing control methods (ie, vector …

Background Differentiating cerebral malaria (CM) from other causes of serious illness in
African children is problematic, owing to the non-specific nature of the clinical presentation …

Cerebral malaria is a dangerous complication of Plasmodium falciparum infection, which
takes a devastating toll on children in sub-Saharan Africa. Although autopsy studies have …