Tobacco and nicotine use

B Le Foll, ME Piper, CD Fowler, S Tonstad… - Nature Reviews …, 2022 - nature.com
Tobacco smoking is a major determinant of preventable morbidity and mortality worldwide.
More than a billion people smoke, and without major increases in cessation, at least half will …

Cannabidiol: pharmacology and therapeutic targets

SC Britch, S Babalonis, SL Walsh - Psychopharmacology, 2021 - Springer
Rationale Cannabidiol (CBD) products lacking regulatory approval are being used to self-
treat a myriad of conditions and for their unsubstantiated health benefits. The scientific …

An update on safety and side effects of cannabidiol: a review of clinical data and relevant animal studies

K Iffland, F Grotenhermen - Cannabis and cannabinoid research, 2017 - liebertpub.com
Introduction: This literature survey aims to extend the comprehensive survey performed by
Bergamaschi et al. in 2011 on cannabidiol (CBD) safety and side effects. Apart from …

Evolution of the Cannabinoid and Terpene Content during the Growth of Cannabis sativa Plants from Different Chemotypes

O Aizpurua-Olaizola, U Soydaner… - Journal of natural …, 2016 - ACS Publications
The evolution of major cannabinoids and terpenes during the growth of Cannabis sativa
plants was studied. In this work, seven different plants were selected: three each from …

Cannabidiol for the treatment of cannabis use disorder: a phase 2a, double-blind, placebo-controlled, randomised, adaptive Bayesian trial

TP Freeman, C Hindocha, G Baio… - The Lancet …, 2020 - thelancet.com
Background A substantial and unmet clinical need exists for pharmacological treatment of
cannabis use disorders. Cannabidiol could offer a novel treatment, but it is unclear which …

A systematic review of cannabidiol dosing in clinical populations

SA Millar, NL Stone, ZD Bellman… - British journal of …, 2019 - Wiley Online Library
Aims Cannabidiol (CBD) is a cannabis‐derived medicinal product with potential application
in a wide‐variety of contexts; however, its effective dose in different disease states remains …

[HTML][HTML] Molecular targets of cannabidiol in neurological disorders

CI Bih, T Chen, AVW Nunn, M Bazelot, M Dallas… - …, 2015 - Elsevier
Cannabis has a long history of anecdotal medicinal use and limited licensed medicinal use.
Until recently, alleged clinical effects from anecdotal reports and the use of licensed …

The therapeutic effects of Cannabis and cannabinoids: An update from the National Academies of Sciences, Engineering and Medicine report

DI Abrams - European journal of internal medicine, 2018 - Elsevier
Abstract The National Academies of Sciences, Engineering and Medicine conducted a rapid
turn-around comprehensive review of recent medical literature on The Health Effects of …

Dosage, efficacy and safety of cannabidiol administration in adults: a systematic review of human trials

C Larsen, J Shahinas - Journal of clinical medicine research, 2020 - pmc.ncbi.nlm.nih.gov
Considering data from in vitro and in vivo studies, cannabidiol (CBD) seems to be a
promising candidate for the treatment of both somatic and psychiatric disorders. The aim of …

[HTML][HTML] The neuropsychopharmacology of cannabis: A review of human imaging studies

MAP Bloomfield, C Hindocha, SF Green… - Pharmacology & …, 2019 - Elsevier
The laws governing cannabis are evolving worldwide and associated with changing
patterns of use. The main psychoactive drug in cannabis is Δ 9-tetrahydrocannabinol (THC) …