Introduction The widespread use of antiretroviral therapies (ART) has increased life
expectancy in HIV patients, predisposing them to chronic non-communicable diseases …

Objective In this study, data regarding epidemiology, risk factors, pathogenesis and outcome
of tenofovir-induced nephrotoxicity will be reviewed, and current and future approaches for …

It is important to realize that guidelines cannot always account for individual variation among
patients. They are not intended to supplant physician judgment with respect to particular …

Background. Tenofovir disoproxil fumarate (TDF) has been linked to renal impairment, but
the extent to which this impairment is reversible is unclear. We aimed to investigate the …

The overall purpose of these guidelines is to provide guidance on best clinical practice in
the treatment and management of adults with HIV infection on antiretroviral therapy (ART) …

Tenofovir disoproxil fumarate (TDF, commonly termed 'tenofovir') is the antiretroviral most
commonly implicated in antiretroviral-induced nephrotoxicity. As patients on successful …

Abstract The Themba Lethu Clinical Cohort was established in 2004 to allow large patient-
level analyses from a single HIV treatment site to evaluate National Treatment Guidelines …

Little evidence is available for the incidence of chronic kidney disease (CKD) and rate of
estimated glomerular filtration rate (eGFR) decrement among Asians with low body weight …

Nephrology is a'Cinderella speciality', a disregarded area of health care, in Africa. Other
health issues have relegated the treatment of kidney diseases to a low priority status, and …

Objective To compare the rate of decline of renal function in tenofovir-and abacavir-based
antiretroviral therapy (ART) in low-body weight treatment-naïve patients with HIV infection …