The multidrug resistance developed in many organisms due to the prolonged use of
antibiotics has been an increasing global health crisis. Klebsiella pneumoniae is a causal …

Background Antimicrobial resistance is a global health issue that requires immediate
attention in terms of new antibiotics and new antibiotic targets. The l-lysine biosynthesis …

In the current study, we show that biofilm formation by various strains and species belonging
to Bifidobacterium, a genus that includes gut commensals with reported health-promoting …

The New Delhi Metallo-β-lactamase (NDM-1) gene makes multiple pathogenic
microorganisms resistant to all known β-lactam antibiotics. The rapid emergence of NDM-1 …

Applying plant-derived fungicides is a safe and sustainable way to control wheat scab. In
this study, volatile organic compounds (VOCs) of wheat cultivars with and without the …

Amino acid metabolism is an important factor in regulating nitrogen source assimilation and
source/sink transport in soybean. Melatonin can improve plant stress resistance, but whether …

In this review, we summarize the recent literature on dapE-encoded N-succinyl-l, l-
diaminopimelic acid desuccinylase (DapE) enzymes, with an emphasis on structure …

Many industrial processes are performed using harmful chemicals. The current technical
synthesis of N-acyl-amino acids relies on acyl chlorides, which are typically obtained from …

DapE is a Zn 2+-metallohydrolase recognized as a drug target for bacterial control. It is a
homodimer that requires the exchange of interface strands by an induced fit essential for …

There is an urgent need for new antibiotics given the rise of antibiotic resistance, and
succinyl-diaminopimelate desuccinylase (DapE, EC 3.5. 1.18) has emerged as a promising …