Clinical reports have highlighted the radical increase of antibiotic resistance. As a result,
multidrug resistance has emerged as a serious threat to human health. Many organic …

Many researchers around the world are working on the development of novel anticancer
drugs with different mechanisms of action. In this case, coumarin is a highly promising …

NIMA related Kinases (NEK7) plays an important role in spindle assembly and mitotic
division of the cell. Over expression of NEK7 leads to the progression of different cancers …

New conjugates of substituted 1, 2, 3-triazoles linked to 1, 2, 4-triazoles were synthesized
starting from the appropriate S-propargylated 1, 2, 4-triazoles 7 and 8. Ligation of 1, 2, 4 …

Tuberculosis, a disease of poverty is a communicable infection with a reasonably high
mortality rate worldwide. 10 Million new cases of TB were reported with approx 1.4 million …

4-Phenyl-3-[2-(phenylamino) ethyl]-1 H-1, 2, 4-triazole-5 (4 H)-thione was used as a starting
compound for the synthesis of the corresponding 1, 2, 4-triazol-3-ylthioacetohydrazide …

Cancer is a multifactorial disease and its genesis and progression are extremely complex.
The biggest problem in the anticancer drug development is acquiring of multidrug resistance …

Today's research is focused on develo** new safe drugs of clinical importance. Nitrogen-
containing heterocycles are abundant in the common of therapeutic scaffolds. Triazoles are …

The JAK-STAT signalling pathway is primarily involved in cytokine signalling and induces
various factors namely, erythropoietin, thrombopoietin, interferons, interleukins, and …

Abstract Crystallization of 1, 2, 4-triazole with (2R, 3R)-(+)-tartaric acid (l (+)-tartaric acid) in a
1: 2 ratio yields the ionic co-crystals of 1, 2, 4-triazolium tartrate–tartaric acid (1: 1),(C 2 H 4 N …