Mussel-inspired chemistry: A promising strategy for natural polysaccharides in biomedical applications

F Liu, X Liu, F Chen, Q Fu - Progress in Polymer Science, 2021 - Elsevier
Polysaccharides are a kind of natural biopolymers and have been widely applied in various
fields, especially biomedical applications, due to their fascinating properties, such as …

Nanoscale metal–organic frameworks for therapeutic, imaging, and sensing applications

K Lu, T Aung, N Guo, R Weichselbaum… - Advanced …, 2018 - Wiley Online Library
Nanotechnology has played an important role in drug delivery and biomedical imaging over
the past two decades. In particular, nanoscale metal–organic frameworks (nMOFs) are …

Pancreatic cancer chemoresistance to gemcitabine

M Amrutkar, IP Gladhaug - Cancers, 2017 - mdpi.com
Pancreatic ductal adenocarcinoma (PDAC), commonly referred to as pancreatic cancer,
ranks among the leading causes of cancer-related deaths in the Western world due to …

Nanoscale MOFs in nanomedicine applications: from drug delivery to therapeutic agents

Z Sun, T Li, T Mei, Y Liu, K Wu, W Le… - Journal of Materials …, 2023 - pubs.rsc.org
Metal–organic frameworks (MOFs) hold great promise for widespread applications in
biomedicine and nanomedicine. MOFs are one of the most fascinating nanocarriers for drug …

Meta-analysis of nanoparticle delivery to tumors using a physiologically based pharmacokinetic modeling and simulation approach

YH Cheng, C He, JE Riviere, NA Monteiro-Riviere… - ACS …, 2020 - ACS Publications
Numerous studies have engineered nanoparticles with different physicochemical properties
to enhance the delivery efficiency to solid tumors, yet the mean and median delivery …

Nanoparticle-mediated combination therapy: two-in-one approach for cancer

S Gurunathan, MH Kang, M Qasim, JH Kim - International journal of …, 2018 - mdpi.com
Cancer represents a group of heterogeneous diseases characterized by uncontrolled
growth and spread of abnormal cells, ultimately leading to death. Nanomedicine plays a …

Nanomedicine applications of hybrid nanomaterials built from metal–ligand coordination bonds: nanoscale metal–organic frameworks and nanoscale coordination …

C He, D Liu, W Lin - Chemical reviews, 2015 - ACS Publications
The past two decades have witnessed rapid developments and innovations in
nanotechnology. 1− 10 Significant efforts have also been devoted to exploring clinical …

Metal–organic frameworks: a future toolbox for biomedicine?

RF Mendes, F Figueira, JP Leite, L Gales… - Chemical Society …, 2020 - pubs.rsc.org
The present review focuses on the use of Metal–Organic Frameworks,(MOFs) highlighting
the most recent developments in the biological field. This review assesses, in the first …

MOF materials as therapeutic agents, drug carriers, imaging agents and biosensors in cancer biomedicine: Recent advances and perspectives

A Bieniek, AP Terzyk, M Wiśniewski, K Roszek… - Progress in Materials …, 2021 - Elsevier
We summarize recent advances in application of MOFs as therapeutic agents, drug carriers,
imaging agents and biosensors in cancer biomedicine. A holistic perspective is adopted to …

Nano codelivery of oxaliplatin and folinic acid achieves synergistic chemo-immunotherapy with 5-fluorouracil for colorectal cancer and liver metastasis

J Guo, Z Yu, M Das, L Huang - ACS nano, 2020 - ACS Publications
FOLFOX, the combinational strategy of folinic acid (FnA), 5-fluorouracil (5-Fu), and
oxaliplatin (OxP), has been used as standard treatment of colorectal cancer (CRC) for …