Recent success in the derivation of haploid embryonic stem cells (haESCs) from mouse via
parthenogenesis and androgenesis has enabled genetic screening in mammalian cells and …

Pluripotent stem cells have been shown to have unique nuclear properties, for example,
hyperdynamic chromatin and large, condensed nucleoli. However, the contribution of the …

Background Many adult tissues contain a population of stem cells with the ability to
regenerate structures similar to the microenvironments from which they are derived in vivo …

Embryonic stem cells (ESCs) possess the capacity to proliferate indefinitely in an
undifferentiated state and to differentiate into various cell types in an organism. However, the …

The mechanisms of self-renewal and pluripotency maintenance of human pluripotent stem
cells (hPSCs) have not been fully elucidated, especially for the role of those poorly …

Embryonic stem (ES) cells have therapeutic potential in regenerative medicine, although the
molecular mechanism controlling their pluripotency is not completely understood …

Ubiquitination and the degradation of the large subunit of RNA polymerase II, Rpb1, is not
only involved in DNA damage-induced arrest but also in other transcription-obstructing …

Topographic features can modulate cell behaviours such as proliferation, migration,
differentiation and apoptosis. Biochemical mechanotransduction implies the conversion of …

Background The human umbilical cord contains mucoid connective tissue and fibroblast-like
cells. These cells named Wharton's jelly cells,(WJCs) display properties similar to …

Embryonic stem cells (ESCs) can undergo unlimited self-renewal and retain pluripotent
developmental potential. The unique characteristics of ESCs, including a distinct …