Both acute and chronic stress can cause allostatic overload, or long-term imbalance in
mediators of homeostasis, that results in disruptions in the maternal-placental-fetal …

Validated biological and psychological markers of acute stress in humans are an important
tool in translational research. The Trier Social Stress Test (TSST), involving public interview …

During pregnancy, programming of the fetal central nervous system establishes
vulnerabilities for emergence of neuropsychiatric phenotypes later in life. Psychosocial …

Postpartum depression (PPD) is a significant mental health concern, especially for women in
vulnerable populations. Oxytocin (OT), a hormone essential for a variety of maternal tasks …

Caregivers of individuals with dementia are at risk for chronic stress and social isolation.
These exogenous factors may lead to perceived stress and perceived loneliness …

Animal studies and a handful of prospective human studies have demonstrated that young
offspring exposed to maternal prenatal stress show abnormalities in immune parameters …

Significant racial health disparities in infant mortality, preterm birth, and infant
neurodevelopment exist in the United States. These disparities highlight a critical public …

Abstract The HEALthy Brain and Child Development (HBCD) Study, a multi-site prospective
longitudinal cohort study, will examine human brain, cognitive, behavioral, social, and …

Depression is the most common complication of childbirth and results in adverse health
outcomes for both mother and child. It is vital, therefore, that health professionals be ready to …

Heightened psychological stress during pregnancy has repeatedly been associated with
increased risk for development of behavior problems and psychiatric disorders in offspring …