Guidelines for the management of severe traumatic brain injury

N Carney, AM Totten, C O'Reilly, JS Ullman… - …, 2017 - journals.lww.com
The scope and purpose of this work is 2-fold: to synthesize the available evidence and to
translate it into recommendations. This document provides recommendations only when …

The far-reaching scope of neuroinflammation after traumatic brain injury

DW Simon, MJ McGeachy, H Bayır, RSB Clark… - Nature Reviews …, 2017 - nature.com
The'silent epidemic'of traumatic brain injury (TBI) has been placed in the spotlight as a result
of clinical investigations and popular press coverage of athletes and veterans with single or …

The European guideline on management of major bleeding and coagulopathy following trauma

R Rossaint, B Bouillon, V Cerny, TJ Coats, J Duranteau… - Critical care, 2016 - Springer
Background Severe trauma continues to represent a global public health issue and mortality
and morbidity in trauma patients remains substantial. A number of initiatives have aimed to …

Traumatic brain injury in China

JY Jiang, GY Gao, JF Feng, Q Mao, LG Chen… - The Lancet …, 2019 - thelancet.com
China has more patients with traumatic brain injury (TBI) than most other countries in the
world, making this condition a major public health concern. Population-based mortality of …

Management of bleeding and coagulopathy following major trauma: an updated European guideline

DR Spahn, B Bouillon, V Cerny, TJ Coats, J Duranteau… - Critical care, 2013 - Springer
Introduction Evidence-based recommendations are needed to guide the acute management
of the bleeding trauma patient. When these recommendations are implemented patient …

Hypothermia for intracranial hypertension after traumatic brain injury

PJD Andrews, HL Sinclair, A Rodriguez… - … England Journal of …, 2015 - Mass Medical Soc
Background In patients with traumatic brain injury, hypothermia can reduce intracranial
hypertension. The benefit of hypothermia on functional outcome is unclear. Methods We …

Effect of early sustained prophylactic hypothermia on neurologic outcomes among patients with severe traumatic brain injury: the POLAR randomized clinical trial

DJ Cooper, AD Nichol, M Bailey, S Bernard… - Jama, 2018 - jamanetwork.com
Importance After severe traumatic brain injury, induction of prophylactic hypothermia has
been suggested to be neuroprotective and improve long-term neurologic outcomes …

Early management of severe traumatic brain injury

JV Rosenfeld, AI Maas, P Bragge… - The Lancet, 2012 - thelancet.com
Severe traumatic brain injury remains a major health-care problem worldwide. Although
major progress has been made in understanding of the pathophysiology of this injury, this …

Critical care management of severe traumatic brain injury in adults

SH Haddad, YM Arabi - Scandinavian journal of trauma, resuscitation and …, 2012 - Springer
Traumatic brain injury (TBI) is a major medical and socio-economic problem, and is the
leading cause of death in children and young adults. The critical care management of …

Brain temperature and its fundamental properties: a review for clinical neuroscientists

H Wang, B Wang, KP Normoyle, K Jackson… - Frontiers in …, 2014 - frontiersin.org
Brain temperature, as an independent therapeutic target variable, has received increasingly
intense clinical attention. To date, brain hypothermia represents the most potent …