Longitudinal sex-at-birth and age analyses of cortical structure in the ABCD Study®
While the brain continues to develop during adolescence, such development may depend
on sex-at-birth. However, the elucidation of such differences may be hindered by analytical …
on sex-at-birth. However, the elucidation of such differences may be hindered by analytical …
Proof-of-concept recall-by-genotype study of extremely low and high Alzheimer's polygenic risk reveals autobiographical deficits and cingulate cortex correlates
Background Genome-wide association studies demonstrate that Alzheimer's disease (AD)
has a highly polygenic architecture, where thousands of independent genetic variants …
has a highly polygenic architecture, where thousands of independent genetic variants …
[HTML][HTML] Dynamics of Cognitive Impairment in MCI Patients over a Three-Year Period: The Informative Role of Blood Biomarkers, Neuroimaging, and Genetic Factors
Given the high growth rates of cognitive decline among the elderly population and the lack
of effective etiological treatments, early diagnosis of cognitive impairment progression is an …
of effective etiological treatments, early diagnosis of cognitive impairment progression is an …
[HTML][HTML] Distinct longitudinal brain white matter microstructure changes and associated polygenic risk of common psychiatric disorders and Alzheimer's disease in the …
Background During the course of adulthood and aging, white matter (WM) structure and
organization are characterized by slow degradation processes such as demyelination and …
organization are characterized by slow degradation processes such as demyelination and …
Identification of novel associations of candidate loci with Alzheimer's disease by leveraging the shared genetic basis with hippocampal volume
C Jiang, SJ van der Lee, N Tesi, WM van der Flier… - medRxiv, 2024 - medrxiv.org
Objective: Alzheimer's disease (AD) is a complex neurodegenerative disorder with a
considerable genetic contribution that remains not fully understood. The hippocampus plays …
considerable genetic contribution that remains not fully understood. The hippocampus plays …
Age-related polygenic effects of Alzheimer's disease on brain structures and cognition in middle aged and elderly adults from UK Biobank
The aetiology of Alzheimer's disease (AD) involves multiple genes and their interactions,
and the polygenetic risk score for AD (AD-PRS) offers a genome-wide assessment of an …
and the polygenetic risk score for AD (AD-PRS) offers a genome-wide assessment of an …
Identificación de posibles dianas terapéuticas en Alzheimer utilizando pipeline bioinformático combinado para aplicarlas al diseño de fármacos asistidos por …
LL Barriga Sanchez - 2023 - repositorio.uta.edu.ec
El acoplamiento molecular demostró que Estradiol y Tricostatina A pueden generar una
inhibición de la proteína CCND1, mientras que Dorsomorfina induce la inhibición de CDK6 …
inhibición de la proteína CCND1, mientras que Dorsomorfina induce la inhibición de CDK6 …
[PDF][PDF] ИНДИВИДУАЛИЗИРОВАННАЯ ПРОГРАММА ПРЕВЕНЦИИ БОЛЕЗНИ АЛЬЦГЕЙМЕРА У ГЕНЕТИЧЕСКИ ПРЕДРАСПОЛОЖЕННОГО ПАЦИЕНТА …
ЮВ Быков, АЮ Быкова, РА Беккер - academia.edu
ИНДИВИДУАЛИЗИРОВАННАЯ ПРОГРАММА ПРЕВЕНЦИИ БОЛЕЗНИ АЛЬЦГЕЙМЕРА
У ГЕН Page 1 13 ИНДИВИДУАЛИЗИРОВАННАЯ ПРОГРАММА ПРЕВЕНЦИИ БОЛЕЗНИ …
У ГЕН Page 1 13 ИНДИВИДУАЛИЗИРОВАННАЯ ПРОГРАММА ПРЕВЕНЦИИ БОЛЕЗНИ …
Genetic architecture of brain morphology and overlap with neuropsychiatric traits
Uncovering the genetic architectures of brain morphology offers valuable insights into brain
development and disease. Genetic association studies of brain morphological phenotypes …
development and disease. Genetic association studies of brain morphological phenotypes …