Synthetic cells: from simple bio‐inspired modules to sophisticated integrated systems

C Guindani, LC da Silva, S Cao, T Ivanov… - Angewandte …, 2022 - Wiley Online Library
Bottom‐up synthetic biology is the science of building systems that mimic the structure and
function of living cells from scratch. To do this, researchers combine tools from chemistry …

Protocells: Milestones and recent advances

I Gözen, ES Köksal, I Põldsalu, L Xue, K Spustova… - Small, 2022 - Wiley Online Library
The origin of life is still one of humankind's great mysteries. At the transition between
nonliving and living matter, protocells, initially featureless aggregates of abiotic matter, gain …

Chemical communication at the synthetic cell/living cell interface

V Mukwaya, S Mann, H Dou - Communications Chemistry, 2021 - nature.com
Although the complexity of synthetic cells has continued to increase in recent years,
chemical communication between protocell models and living organisms remains a key …

Peptide‐based coacervate‐core vesicles with semipermeable membranes

M Abbas, JO Law, SN Grellscheid… - Advanced …, 2022 - Wiley Online Library
Coacervates droplets have long been considered as potential protocells to mimic living
cells. However, these droplets lack a membrane and are prone to coalescence, limiting their …