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[HTML][HTML] Pathophysiology and therapeutic approaches for spinal cord injury
Spinal cord injury (SCI) is a disabling condition that disrupts motor, sensory, and autonomic
functions. Despite extensive research in the last decades, SCI continues to be a global …
functions. Despite extensive research in the last decades, SCI continues to be a global …
A comprehensive look at the psychoneuroimmunoendocrinology of spinal cord injury and its progression: mechanisms and clinical opportunities
MA Ortega, O Fraile-Martinez, C García-Montero… - Military Medical …, 2023 - Springer
Spinal cord injury (SCI) is a devastating and disabling medical condition generally caused
by a traumatic event (primary injury). This initial trauma is accompanied by a set of biological …
by a traumatic event (primary injury). This initial trauma is accompanied by a set of biological …
[HTML][HTML] Functional hydrogels as therapeutic tools for spinal cord injury: New perspectives on immunopharmacological interventions
Spinal cord injury (SCI) is a complex medical and psychological challenge for which there is
no curative therapy currently available. Despite major progress in pharmacological and …
no curative therapy currently available. Despite major progress in pharmacological and …
Filling the gap: neural stem cells as a promising therapy for spinal cord injury
Spinal cord injury (SCI) can lead to severe motor, sensory and social impairments having a
huge impact on patients' lives. The complex and time-dependent SCI pathophysiology has …
huge impact on patients' lives. The complex and time-dependent SCI pathophysiology has …
Recent advances in the regenerative approaches for traumatic spinal cord injury: materials perspective
Spinal cord injury (SCI) is a devastating health condition that may lead to permanent
disabilities and death. Understanding the pathophysiological perspectives of traumatic SCI …
disabilities and death. Understanding the pathophysiological perspectives of traumatic SCI …
Neurotrauma—From injury to repair: Clinical perspectives, cellular mechanisms and promoting regeneration of the injured brain and spinal cord
Traumatic injury to the brain and spinal cord (neurotrauma) is a common event across
populations and often causes profound and irreversible disability. Pathophysiological …
populations and often causes profound and irreversible disability. Pathophysiological …
[HTML][HTML] A therapeutic matrix: virtual reality as a clinical tool for spinal cord injury-induced neuropathic pain
Neuropathic pain (NP) is a chronic, debilitating, and resistant form of pain. The onset rate of
NP following spinal cord injuries (SCI) is high and may reduce the quality of life more than …
NP following spinal cord injuries (SCI) is high and may reduce the quality of life more than …
Chronic pain after spinal cord injury: is there a role for neuron-immune dysregulation?
SS Chambel, I Tavares, CD Cruz - Frontiers in Physiology, 2020 - frontiersin.org
Spinal cord injury (SCI) is a devastating event with a tremendous impact in the life of the
affected individual and family. Traumatic injuries related to motor vehicle accidents, falls …
affected individual and family. Traumatic injuries related to motor vehicle accidents, falls …
Pre-clinical assessment of roflumilast Therapy in a thoracic model of Spinal cord Injury
The failure of axons to regenerate after a spinal cord injury (SCI) remains one of the greatest
challenges in neuroscience. The initial mechanical trauma is followed by a secondary injury …
challenges in neuroscience. The initial mechanical trauma is followed by a secondary injury …
The secretome of macrophages has a differential impact on spinal cord injury recovery according to the polarization protocol
J Lentilhas-Graça, DJ Santos, J Afonso… - Frontiers in …, 2024 - frontiersin.org
Introduction The inflammatory response after spinal cord injury (SCI) is an important
contributor to secondary damage. Infiltrating macrophages can acquire a spectrum of …
contributor to secondary damage. Infiltrating macrophages can acquire a spectrum of …