Clinical application and detection techniques of liquid biopsy in gastric cancer

S Ma, M Zhou, Y Xu, X Gu, M Zou, G Abudushalamu… - Molecular cancer, 2023 - Springer
Gastric cancer (GC) is one of the most common tumors worldwide and the leading cause of
tumor-related mortality. Endoscopy and serological tumor marker testing are currently the …

Biomarkers for diagnosis and therapeutic options in hepatocellular carcinoma

YT Chan, C Zhang, J Wu, P Lu, L Xu, H Yuan, Y Feng… - Molecular Cancer, 2024 - Springer
Liver cancer is a global health challenge, causing a significant social-economic burden.
Hepatocellular carcinoma (HCC) is the predominant type of primary liver cancer, which is …

Liquid biopsy in gastric cancer: predictive and prognostic biomarkers

Z Zhang, H Wu, W Chong, L Shang, C **g, L Li - Cell death & disease, 2022 - nature.com
Gastric cancer (GC) is a high-incidence cancer worldwide. Most patients are diagnosed at
an advanced stage, by which time they have limited treatment options and poor prognosis …

Shifting the cancer screening paradigm: the rising potential of blood-based multi-cancer early detection tests

T Brito-Rocha, V Constâncio, R Henrique, C Jerónimo - Cells, 2023 - mdpi.com
Cancer remains a leading cause of death worldwide, partly owing to late detection which
entails limited and often ineffective therapeutic options. Most cancers lack validated …

Stool and blood biomarkers for colorectal cancer management: an update on screening and disease monitoring

A Mannucci, A Goel - Molecular Cancer, 2024 - Springer
Background Biomarkers have revolutionized the management of colorectal cancer (CRC),
facilitating early detection, prevention, personalized treatment, and minimal residual disease …

Predictive performance of cell-free nucleic acid-based multi-cancer early detection tests: a systematic review

E LeeVan, P Pinsky - Clinical Chemistry, 2024 - academic.oup.com
Background Cancer-screening tests that can detect multiple cancer types, or multi-cancer
early detection (MCED) tests, have emerged recently as a potential new tool in decreasing …

Circulating cell-free DNA-based multi-cancer early detection

K Zhang, R Fu, R Liu, Z Su - Trends in Cancer, 2024 - cell.com
Patients benefit considerably from early detection of cancer. Existing single-cancer tests
have various limitations, which could be effectively addressed by circulating cell-free DNA …

Liquid biopsy in lung cancer: biomarkers for the management of recurrence and metastasis

VGP Souza, A Forder, LJ Brockley… - International Journal of …, 2023 - mdpi.com
Liquid biopsies have emerged as a promising tool for the detection of metastases as well as
local and regional recurrence in lung cancer. Liquid biopsy tests involve analyzing a …

Screening for pancreatic cancer has the potential to save lives, but is it practical?

BL Mazer, JW Lee, NJ Roberts, LC Chu… - Expert review of …, 2023 - Taylor & Francis
Introduction Most patients with pancreatic cancer present with advanced stage, incurable
disease. However, patients with high-grade precancerous lesions and many patients with …

Bidirectional mediation effects between intratumoral microbiome and host DNA methylation changes contribute to stomach adenocarcinoma

K Yue, D Sheng, X Xue, L Zhao, G Zhao… - Microbiology …, 2023 - journals.asm.org
The induction of aberrant DNA methylation is the major pathway by which Helicobacter
pylori infection induces stomach adenocarcinoma (STAD). The involvement of the non-H …