Chronic obstructive pulmonary disease in never-smokers: risk factors, pathogenesis, and implications for prevention and treatment

IA Yang, CR Jenkins, SS Salvi - The Lancet Respiratory Medicine, 2022 - thelancet.com
Chronic obstructive pulmonary disease (COPD) was traditionally thought to be caused by
tobacco smoking. However, recognition of the importance of non-smoking-related risk …

An update on immunologic mechanisms in the respiratory mucosa in response to air pollutants

RD Huff, C Carlsten, JA Hirota - Journal of allergy and clinical immunology, 2019 - Elsevier
Every day, we breathe in more than 10,000 L of air that contains a variety of air pollutants
that can pose negative consequences to lung health. The respiratory mucosa formed by the …

The effects and pathogenesis of PM2. 5 and its components on chronic obstructive pulmonary disease

Q Wang, S Liu - … Journal of Chronic Obstructive Pulmonary Disease, 2023 - Taylor & Francis
Chronic obstructive pulmonary disease (COPD), a heterogeneous disease, is the leading
cause of death worldwide. In recent years, air pollution, especially particulate matter (PM) …

[HTML][HTML] Effective-component compatibility of Bufei Yishen formula protects COPD rats against PM2. 5-induced oxidative stress via miR-155/FOXO3a pathway

J Li, J Wang, Y Li, P Zhao, Y Tian, X Liu, H He… - … and Environmental Safety, 2021 - Elsevier
Abstract Ambient particulate matter< 2.5 µm (PM2. 5) has been identified as a critical risk
factor in chronic obstructive pulmonary disease (COPD) exacerbation, but therapies for this …

Molecular mechanisms of N-acetylcysteine in RSV infections and air pollution-induced alterations: a sco** review

A Wrotek, A Badyda, T Jackowska - International Journal of Molecular …, 2024 - mdpi.com
N-acetylcysteine (NAC) is a mucolytic agent with antioxidant and anti-inflammatory
properties. The respiratory syncytial virus (RSV) is one of the most important etiological …

Multivariate analysis of performance and emission parameters in a diesel engine using biodiesel and oxygenated additive

M Jafari, P Verma, TA Bodisco, A Zare… - Energy Conversion and …, 2019 - Elsevier
Rising concerns over environmental and health issues of internal combustion engines,
along with growing energy demands, have motivated investigation into alternative fuels …

Lung fibroblasts from chronic obstructive pulmonary disease subjects have a deficient gene expression response to cigarette smoke extract compared to healthy

M Garcia-Ryde, NMD van der Burg… - … journal of chronic …, 2023 - Taylor & Francis
Background and aim Cigarette smoking is the most common cause of chronic obstructive
pulmonary disease (COPD) but more mechanistic studies are needed. Cigarette smoke …

Influence of dose and exposition time in the effectiveness of N-Acetyl-L-cysteine treatment in A549 human epithelial cells

P Montero, I Roger, C Estornut, J Milara, J Cortijo - Heliyon, 2023 - cell.com
Abstract N-Acetyl-l-cysteine (NAC) acts as a precursor of the tripeptide glutathione (GSH),
one of the principal cell mechanisms for reactive oxygen species (ROS) detoxification …

Effects of endogenous and exogenous reductants in lung fluid on the bioaccessible metal concentration and oxidative potential of ultrafine particles

Y Yu, T Zhu - Science of The Total Environment, 2023 - Elsevier
Health risk posed by ultrafine particles (UFPs) is potentially increased by reducing
substances present in lung fluid, although knowledge of the underlying mechanisms is …

Dietary supplementations to mitigate the cardiopulmonary effects of air pollution toxicity: A systematic review of clinical trials

M Ilaghi, F Kafi, M Shafiei, M Zangiabadian, MJ Nasiri - Plos one, 2024 - journals.plos.org
Background There is a consistent association between exposure to air pollution and
elevated rates of cardiopulmonary illnesses. As public health activities emphasize the …