Therapeutic targets in lung tissue remodelling and fibrosis

G Liu, AM Philp, T Corte, MA Travis, H Schilter… - Pharmacology & …, 2021 - Elsevier
Structural changes involving tissue remodelling and fibrosis are major features of many
pulmonary diseases, including asthma, chronic obstructive pulmonary disease (COPD) and …

Pathogenesis, clinical features of asthma COPD overlap, and therapeutic modalities

S Dey, MS Eapen, C Chia… - … of Physiology-Lung …, 2022 - journals.physiology.org
Both asthma and COPD are heterogeneous diseases identified by characteristic symptoms
and functional abnormalities, with airway obstruction common in both diseases. Asthma …

Role of lung microbiome in innate immune response associated with chronic lung diseases

KR Paudel, V Dharwal, VK Patel, I Galvao… - Frontiers in …, 2020 - frontiersin.org
Respiratory diseases such as asthma, chronic obstructive pulmonary disease (COPD), lung
fibrosis, and lung cancer, pose a huge socio-economic burden on society and are one of the …

The effects of epithelial–mesenchymal transitions in COPD induced by cigarette smoke: an update

X Su, W Wu, Z Zhu, X Lin, Y Zeng - Respiratory research, 2022 - Springer
Cigarette smoke is a complex aerosol containing a large number of compounds with a
variety of toxicity and carcinogenicity. Long-term exposure to cigarette smoke significantly …

Molecular aspects and therapeutic implications of herbal compounds targeting different types of cancer

A Sharma, L Sharma, SK Nandy, N Payal, S Yadav… - Molecules, 2023 - mdpi.com
Due to genetic changes in DNA (deoxyribonucleic acid) sequences, cancer continues to be
the second most prevalent cause of death. The traditional target-directed approach, which is …

From COPD to lung cancer: mechanisms linking, diagnosis, treatment, and prognosis

C Qi, SW Sun, XZ **ong - International journal of chronic …, 2022 - Taylor & Francis
Many studies have proved that the pathogenesis of the chronic obstructive pulmonary
disease (COPD) and lung cancer is related, and may cause and affect each other to a …

impact of cigarette smoking on intestinal inflammation—direct and indirect mechanisms

S Papoutsopoulou, J Satsangi… - Alimentary …, 2020 - Wiley Online Library
Background The inflammatory bowel diseases, Crohn's disease and ulcerative colitis are
related multifactorial diseases. Their pathogenesis is influenced by each individual's …

Dissecting the in vitro fate of plant-derived bioactive encapsulated nanoparticles in lung diseases

AB Saeid, VK Patel, S Mehndiratta, R Rajput… - Food Bioscience, 2023 - Elsevier
Lung diseases such as asthma, chronic obstructive pulmonary disease (COPD), and lung
cancer are prevalent worldwide, with high mortality rates. There are many pathways …

Alterations of lung microbiota in patients with non-small cell lung cancer

W Zeng, CZ Zhao, M Yu, H Chen, Y Pan, Y Wang… - …, 2022 - Taylor & Francis
The role of lung microbiota in non-small cell lung cancer remains unclear. We investigated
the characteristics and functional roles of lung microbiota in non-small cell lung cancer …

The lung microbiome in COPD and lung cancer: Exploring the potential of metal-based drugs

M O'Shaughnessy, O Sheils, AM Baird - International Journal of …, 2023 - mdpi.com
Chronic obstructive pulmonary disease (COPD) and lung cancer 17 are two of the most
prevalent and debilitating respiratory diseases worldwide, both associated with high …