Biomaterials have played an increasingly prominent role in the success of biomedical
devices and in the development of tissue engineering, which seeks to unlock the …

Hydrogels, microgels and nanogels have emerged as versatile and viable platforms for
sustained protein release, targeted drug delivery, and tissue engineering due to excellent …

ABSTRACT Thiol–norbornene (thiol–ene) photoclick hydrogels have emerged as a diverse
material system for tissue engineering applications. These hydrogels are crosslinked …

Covalently cross-linked gelatin hydrogels have received considerable attention in
biomedical fields due to the inherent bioactivity of gelatin and the stability of covalent bonds …

Abstract Three-dimensional (3D) cultures use the property of some cells to self-organize in
matrices and generate structures that can be programmed to represent an organ or a …

Human embryonic stem cells (hESC) and induced pluripotent stem cells (hiPSC) are
considered attractive sources of pancreatic β cells and islet organoids. Recently, several …

Enzymatically-degradable materials recapitulate the dynamic and reciprocal interactions
between cells and their native microenvironment by allowing cells to actively shape the …

Numerous studies to date have contributed to a paradigm shift in modeling cancer, moving
from the traditional two-dimensional culture system to three-dimensional (3D) culture …

Over the past two decades in situ tissue engineering has emerged as a new approach
where biomaterials are used to harness the body's own stem/progenitor cells to regenerate …

The tumor microenvironment (TME) governs all aspects of cancer progression and in vitro
3D cell culture platforms are increasingly developed to emulate the interactions between …