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Transition metals-catalyzed amination of biomass feedstocks for sustainable construction of N-heterocycles
Q Yan, X Wu, H Jiang, H Wang, F Xu, H Li… - Coordination Chemistry …, 2024 - Elsevier
Transition metals, which are of diversity in their bonding orbitals, have a variety of significant
oxidation states and more complex chemical properties compared to the main group metals …
oxidation states and more complex chemical properties compared to the main group metals …
Recent advances in the transition metal catalyzed synthesis of quinoxalines: a review
Quinoxalines are a class of N-heterocycles which are present in a variety of natural and
synthetic compounds. They act as a versatile building block in synthesizing novel …
synthetic compounds. They act as a versatile building block in synthesizing novel …
LVVO-Ethyl Maltol-Based Metallodrugs (L2– = Tridentate ONO Ligands): Hydrophobicity, Hydrolytic Stability, and Cytotoxicity via ROS-Mediated Apoptosis
Four new oxidovanadium [VVOL1–4 (ema)] complexes (1–4) have been synthesized using
tridentate binegative ONO donor ligands H2L1–4 [H2L1:(E)-N′-(2-hydroxybenzylidene) …
tridentate binegative ONO donor ligands H2L1–4 [H2L1:(E)-N′-(2-hydroxybenzylidene) …
DNA intercalators as anticancer agents
Cancer is one of the most prevailing disease conditions, which occurs due to uncontrolled
cell division either due to natural mutation to the genes or due to changes induced by …
cell division either due to natural mutation to the genes or due to changes induced by …
Design, synthesis, molecular docking and anti-proliferative evaluations of [1, 2, 4] triazolo [4, 3-a] quinoxaline derivatives as DNA intercalators and Topoisomerase II …
In view of their DNA intercalation activities as anticancer agents, novel twenty four [1, 2, 4]
triazolo [4, 3-a] quinoxaline derivatives have been designed, synthesized and evaluated …
triazolo [4, 3-a] quinoxaline derivatives have been designed, synthesized and evaluated …
[1, 2, 4] Triazolo [4, 3-a] quinoxaline and [1, 2, 4] triazolo [4, 3-a] quinoxaline-1-thiol-derived DNA intercalators: design, synthesis, molecular docking, in silico ADMET …
In view of their DNA intercalation activities as anticancer agents, 17 novel [1, 2, 4] triazolo [4,
3-a] quinoxaline derivatives have been designed, synthesized and evaluated against …
3-a] quinoxaline derivatives have been designed, synthesized and evaluated against …
Mono-quinoxaline-induced DNA structural alteration leads to ZBP1/RIP3/MLKL-driven necroptosis in cancer cells
Evading the cellular apoptosis mechanism by modulating multiple pathways poses a sturdy
barrier to effective chemotherapy. Cancer cell adeptly resists the apoptosis signaling …
barrier to effective chemotherapy. Cancer cell adeptly resists the apoptosis signaling …
Insights into the Theranostic Activity of Nonoxido VIV: Lysosome-Targeted Anticancer Metallodrugs
Develo** new anticancer agents can be useful, with the ability to diagnose and treat
cancer worldwide. Previously, we focused on examining the effects of nonoxidovanadium …
cancer worldwide. Previously, we focused on examining the effects of nonoxidovanadium …
Isatin-indoloquinoxaline click adducts with a potential to overcome platinum-based drug-resistance in ovarian cancer
Herein, a series of isatin tethered indolo [2, 3-b] quinoxaline hybrids was synthesized by
considering the pharmacophoric features of known DNA intercalators and topoisomerase II …
considering the pharmacophoric features of known DNA intercalators and topoisomerase II …
Magnetic proline-based ionic liquid surfactant as a nano-carrier for hydrophobic drug delivery
Magnetic proline-based surface-active ionic liquid ([ProC10][FeCl3Br]) have been
synthesized and investigated for their application in hydrophobic drug delivery. Hydrophobic …
synthesized and investigated for their application in hydrophobic drug delivery. Hydrophobic …