Bioactive materials that promote the homing of endogenous mesenchymal stem cells to improve Wound Healing

Z Jiang, L Chen, L Huang, S Yu, J Lin, M Li… - International Journal …, 2024 - Taylor & Francis
Endogenous stem cell homing refers to the transport of endogenous mesenchymal stem
cells (MSCs) to damaged tissue. The paradigm of using well-designed biomaterials to …

Physical modulation of mesenchymal stem cell exosomes: A new perspective for regenerative medicine

D Wu, X Zhao, J **e, R Yuan, Y Li, Q Yang… - Cell …, 2024 - Wiley Online Library
Mesenchymal stem cell‐derived exosomes (MSC‐Exo) offer promising therapeutic potential
for various refractory diseases, presenting a novel therapeutic strategy. However, their …

κ-Carrageenan/konjac glucomannan composite hydrogel-based 3D porcine cultured meat production

X Gu, S Hua, Y Huang, S Liu, Y Wang, M Zhou… - Food …, 2024 - Elsevier
Alternative technology for cultured meat production holds the potential to alleviate ethical,
environmental, and public health concerns stemming from conventional husbandry. As a key …

Extracellular fluid viscosity regulates human mesenchymal stem cell lineage and function

A Amitrano, Q Yuan, B Agarwal, A Sen, YW Dance… - Science …, 2025 - science.org
Human mesenchymal stem cells (hMSCs) respond to mechanical stimuli, including stiffness
and viscoelasticity. To date, it is unknown how extracellular fluid viscosity affects hMSC …

An instructional design strategy for optimization of GelMA hydrogels material properties

S Ding, S He, L Shen, Q Yang, G Yang - European Polymer Journal, 2024 - Elsevier
Gelatin methacryloyl (GelMA) hydrogels have become a key biomaterial in various
biomedical fields, such as tissue regeneration engineering and drug delivery, due to their …

Spatial dimension cues derived from fibrous scaffolds trigger mechanical activation to potentiate the paracrine and regenerative functions of MSCs via the FAK-PI3K …

S Xu, M Zhang, R Wang, J Zhang, C Wang, L **e… - Acta Biomaterialia, 2024 - Elsevier
Secretomes from mesenchymal stem cells (MSCs) have significant therapeutic potential and
could be the basis for future MSCs treatments. Innovative design of the topology of …

[HTML][HTML] Bone cell response to additively manufactured 3D micro-architectures with controlled Poisson's ratio: Auxetic vs. non-auxetic meta-biomaterials

E Yarali, M Klimopoulou, K David, PE Boukany… - Acta Biomaterialia, 2024 - Elsevier
The Poisson's ratio and elastic modulus are two parameters determining the elastic behavior
of biomaterials. While the effects of elastic modulus on the cell response is widely studied …

Biomaterials for Cell Manufacturing

RC Miller, JS Temenoff - ACS Macro Letters, 2024 - ACS Publications
Cell therapies, potent populations of cells used to treat disease and injury, can be
strategically manufactured with biomaterial intervention to improve clinical translation. In this …

[HTML][HTML] Vitrification of 3D-MSCs encapsulated in GelMA hydrogel: Improved cryosurvival, reduced cryoprotectant concentration, and enhanced wound healing

Z Pu, L Zhang, H Yang, T Shao, D Wang… - International Journal of …, 2025 - Elsevier
Compared to traditional 2D-cultured mesenchymal stem cells (MSCs), 3D-MSCs offer
distinct advantages in disease treatment. However, large-scale culture of 3D-MSCs remains …

A thermosensitive hydrogel for the sustained delivery of exosomes extracted from menstrual blood mesenchymal stem cells and frizzled antibody on triple-negative …

F Hasannejad, M Bahraminasab, L Farahmand… - Journal of Drug Delivery …, 2024 - Elsevier
Due to the heterogeneity of triple-negative breast cancer (TNBC), conventional treatments
usually respond poorly and effective targeted therapies for this type of cancer are rare. Wnt …