The head and neck district represents one of the most frequent sites of cancer, and the
percentage of metastases is very high in both loco-regional and distant areas. Prognosis …

Simple Summary Head and neck cancer (HNC) is the sixth most common cancer, causing
almost half a million deaths worldwide every year. The two subtypes of HNC are distinctly …

Treatment is complex for patients with head and neck (H&N) cancers with specific site of
disease, stage, and pathologic findings guiding treatment decision-making. Treatment …

Context Human papillomavirus (HPV) is a major cause of oropharyngeal squamous cell
carcinomas, and HPV (and/or surrogate marker p16) status has emerged as a prognostic …

PURPOSE Plasma circulating tumor human papillomavirus DNA (ctHPVDNA) is a sensitive
and specific biomarker of human papillomavirus (HPV)-associated oropharyngeal …

Purpose: This study aimed to assess the antitumor activity and safety of neoadjuvant
chemotherapy combined with PD-1 inhibitor camrelizumab in patients with locally advanced …

Purpose: Despite generally favorable outcomes, 15% to 25% of patients with human
papillomavirus (HPV)-driven oropharyngeal squamous cell carcinoma (OPSCC) will have …

Background Development of evidence‐based post‐treatment surveillance guidelines in
recurrent/metastatic head and neck squamous cell carcinoma (R/M HNSCC) is limited by …

Importance Human papillomavirus (HPV)–positive oropharyngeal squamous cell carcinoma
has an overall favorable prognosis, yet a subset of patients will experience devastating …

Epidemiological and clinical studies over the past two decades have provided strong
evidence that genetic elements interacting with environmental components can individually …