Due to the emerging bacterial resistance and the protection of tenacious biofilms, it is hard
for the single antibacterial modality to achieve satisfactory therapeutic effects nowadays. In …

Nanotechnology is a growing field, with many potential biomedical applications of
nanomedicine for the treatment of different diseases, particularly cancer, on the horizon …

Despite the challenges posed by drug resistance and side effects, chemotherapy remains a
pivotal strategy in cancer treatment. A key issue in this context is macroautophagy …

Chemoresistance and metastasis are the major challenges for the current ovarian cancer
treatment. Understanding the mechanisms of ovarian cancer progression and metastasis is …

Oxaliplatin (OXA) resistance is the major obstacle to the anticancer effects of chemotherapy
in colorectal cancer (CRC) patients. MicroRNAs (miRNAs) play an important role in the …

Normal cells depend on autophagy to maintain cellular homeostasis by recycling damaged
organelles and misfolded proteins and degrading toxic agents. Similar to apoptosis …

Despite significant advances in early detection and personalized treatment, cancer is still
among the leading causes of death globally. One of the possible anticancer approaches that …

Conspectus Autophagy is a critical lysosome-mediated cellular degradation process for the
clearance of damaged organelles, obsolete proteins, and invading pathogens and plays …

Drug delivery for successful treatment of cancer, which is potently facilitated by progress in
nanotechnology opens new avenue in this field. Graphene oxide (GO) and its derivatives, as …

Although cisplatin is one of the most common antineoplastic drug, its successful utilisation in
cancer treatment is limited by the drug resistance. Multiple attempts have been made to find …