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Ferritin: a promising nanoreactor and nanocarrier for bionanotechnology
The essence of bionanotechnology lies in the application of nanotechnology/nanomaterials
to solve the biological problems. Quantum dots and nanoparticles hold potential biomedical …
to solve the biological problems. Quantum dots and nanoparticles hold potential biomedical …
The tuberculosis drug discovery and development pipeline and emerging drug targets
K Mdluli, T Kaneko, A Upton - Cold Spring …, 2015 - perspectivesinmedicine.cshlp.org
The recent accelerated approval for use in extensively drug-resistant and multidrug-resistant-
tuberculosis (MDR-TB) of two first-in-class TB drugs, bedaquiline and delamanid, has …
tuberculosis (MDR-TB) of two first-in-class TB drugs, bedaquiline and delamanid, has …
Tuberculosis drug discovery and emerging targets
K Mdluli, T Kaneko, A Upton - … of the New York Academy of …, 2014 - Wiley Online Library
Current tuberculosis (TB) therapies take too long and the regimens are complex and subject
to adverse effects and drug–drug interactions with concomitant medications. The emergence …
to adverse effects and drug–drug interactions with concomitant medications. The emergence …
Modification of 4-Fold and B-Pores in Bacterioferritin from Mycobacterium tuberculosis Reveals Their Role in Fe2+ Entry and Oxidoreductase Activity
The self-assembled ferritin nanocages, nature's solution to iron toxicity and its low solubility,
scavenge free iron to synthesize hydrated ferric oxyhydroxide mineral inside their central …
scavenge free iron to synthesize hydrated ferric oxyhydroxide mineral inside their central …
Iron Mineralizing Bacterioferritin A from Mycobacterium tuberculosis Exhibits Unique Catalase-Dps-like Dual Activities
Mycobacterium tuberculosis (Mtb) expresses heme binding protein nanocages,
bacterioferritin A (BfrA), along with nonheme bacterioferritin B (BfrB). BfrA is unique to …
bacterioferritin A (BfrA), along with nonheme bacterioferritin B (BfrB). BfrA is unique to …
Alteration of Coaxial Heme Ligands Reveals the Role of Heme in Bacterioferritin from Mycobacterium tuberculosis
The uptake and utilization of iron remains critical for the survival/virulence of the
host/pathogens in spite of the limitations (low bioavailability/high toxicity) associated with …
host/pathogens in spite of the limitations (low bioavailability/high toxicity) associated with …
Impact of Phosphate on Iron Mineralization and Mobilization in Nonheme Bacterioferritin B from Mycobacterium tuberculosis
Ferritins are supramolecular nanocage proteins, which synthesize hydrated ferric
oxyhydroxide mineral via protein mediated rapid Fe2+ sequestration and ferroxidase …
oxyhydroxide mineral via protein mediated rapid Fe2+ sequestration and ferroxidase …
Crystal Structure of Bfr A from Mycobacterium tuberculosis: Incorporation of Selenomethionine Results in Cleavage and Demetallation of Haem
Emergence of tuberculosis as a global health threat has necessitated an urgent search for
new antitubercular drugs entailing determination of 3-dimensional structures of a large …
new antitubercular drugs entailing determination of 3-dimensional structures of a large …
Heterogeneity in thylakoid membrane proteome of Synechocystis 6803
Cell-free extracts of Synechocystis 6803 were fractionated by successive ultracentrifugation
at 40,000× g, 90,000× g and 150,000× g to obtain the three thylakoid fractions designated as …
at 40,000× g, 90,000× g and 150,000× g to obtain the three thylakoid fractions designated as …
Anti-tuberculosis therapy: Urgency for new drugs and integrative approach
L Jena, BC Harinath - Biomedical and Biotechnology Research …, 2018 - journals.lww.com
Tuberculosis (TB) remains the major health problem causing morbidity and mortality
throughout the world. Increase in multidrug resistant, extensively drug-resistant, and totally …
throughout the world. Increase in multidrug resistant, extensively drug-resistant, and totally …