[HTML][HTML] The SLC9A-C mammalian Na+/H+ exchanger family: molecules, mechanisms, and physiology
SF Pedersen, L Counillon - Physiological reviews, 2019 - journals.physiology.org
Na+/H+ exchangers play pivotal roles in the control of cell and tissue pH by mediating the
electroneutral exchange of Na+ and H+ across cellular membranes. They belong to an …
electroneutral exchange of Na+ and H+ across cellular membranes. They belong to an …
Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals
Here we conducted a large-scale genetic association analysis of educational attainment in a
sample of approximately 1.1 million individuals and identify 1,271 independent genome …
sample of approximately 1.1 million individuals and identify 1,271 independent genome …
Development of dendritic form and function
The nervous system is populated by numerous types of neurons, each bearing a dendritic
arbor with a characteristic morphology. These type-specific features influence many aspects …
arbor with a characteristic morphology. These type-specific features influence many aspects …
[HTML][HTML] Satb1 regulates contactin 5 to pattern dendrites of a mammalian retinal ganglion cell
The size and shape of dendritic arbors are prime determinants of neuronal connectivity and
function. We asked how ON-OFF direction-selective ganglion cells (ooDSGCs) in mouse …
function. We asked how ON-OFF direction-selective ganglion cells (ooDSGCs) in mouse …
Camkiiβ in neuronal development and plasticity: An emerging candidate in brain diseases
The calcium/calmodulin-dependent protein kinase II (CaMKII) is a ubiquitous and central
player in Ca2+ signaling that is best known for its functions in the brain. In particular, the α …
player in Ca2+ signaling that is best known for its functions in the brain. In particular, the α …
In vivo imaging of dendritic pruning in dentate granule cells
We longitudinally imaged the develo** dendrites of adult-born mouse dentate granule
cells (DGCs) in vivo and found that they underwent over-branching and pruning. Exposure …
cells (DGCs) in vivo and found that they underwent over-branching and pruning. Exposure …
Glutamate-induced and NMDA receptor-mediated neurodegeneration entails P2Y1 receptor activation
AP Simões, CG Silva, JM Marques, D Pochmann… - Cell Death & …, 2018 - nature.com
Despite the characteristic etiologies and phenotypes, different brain disorders rely on
common pathogenic events. Glutamate-induced neurotoxicity is a pathogenic event shared …
common pathogenic events. Glutamate-induced neurotoxicity is a pathogenic event shared …
Deterministic and stochastic rules of branching govern dendrite morphogenesis of sensory neurons
Dendrite morphology is necessary for the correct integration of inputs that neurons receive.
The branching mechanisms allowing neurons to acquire their type-specific morphology …
The branching mechanisms allowing neurons to acquire their type-specific morphology …
[HTML][HTML] Glomerular development–sha** the multi-cellular filtration unit
C Schell, N Wanner, TB Huber - Seminars in cell & developmental biology, 2014 - Elsevier
The glomerulus represents a highly structured filtration unit, composed of glomerular
endothelial cells, mesangial cells, podocytes and parietal epithelial cells. During …
endothelial cells, mesangial cells, podocytes and parietal epithelial cells. During …
Regulation of neuronal connectivity in the mammalian brain by chromatin remodeling
Highlights•Chd chromatin remodeling enzymes govern distinct phases of neuronal
connectivity.•Chd4 orchestrates afferent and efferent neuronal connectivity via distinct …
connectivity.•Chd4 orchestrates afferent and efferent neuronal connectivity via distinct …