Brain MRI atrophy quantification in MS: from methods to clinical application
Patients with the main clinical phenotypes of multiple sclerosis (MS) manifest varying
degrees of brain atrophy beyond that of normal aging. Assessment of atrophy helps to …
degrees of brain atrophy beyond that of normal aging. Assessment of atrophy helps to …
Deep gray matter volume loss drives disability worsening in multiple sclerosis
Objective Gray matter (GM) atrophy occurs in all multiple sclerosis (MS) phenotypes. We
investigated whether there is a spatiotemporal pattern of GM atrophy that is associated with …
investigated whether there is a spatiotemporal pattern of GM atrophy that is associated with …
Progression of regional grey matter atrophy in multiple sclerosis
Abstract See Stankoff and Louapre (doi: 10.1093/brain/awy114) for a scientific commentary
on this article. Grey matter atrophy is present from the earliest stages of multiple sclerosis …
on this article. Grey matter atrophy is present from the earliest stages of multiple sclerosis …
The role of T1-weighted derived measures of neurodegeneration for assessing disability progression in multiple sclerosis
Introduction Multiple sclerosis (MS) is characterised by the accumulation of permanent
neurological disability secondary to irreversible tissue loss (neurodegeneration) in the brain …
neurological disability secondary to irreversible tissue loss (neurodegeneration) in the brain …
Cortical atrophy patterns in multiple sclerosis are non-random and clinically relevant
Abstract See Chard and Miller (doi: 10.1093/brain/awv354) for a scientific commentary on
this article. Grey matter atrophy is common in multiple sclerosis. However, in contrast with …
this article. Grey matter atrophy is common in multiple sclerosis. However, in contrast with …
[HTML][HTML] Gray matter atrophy patterns in multiple sclerosis: a 10-year source-based morphometry study
Objectives To investigate spatial patterns of gray matter (GM) atrophy and their association
with disability progression in patients with early relapsing-remitting multiple sclerosis (MS) in …
with disability progression in patients with early relapsing-remitting multiple sclerosis (MS) in …
CSF levels of CXCL12 and osteopontin as early markers of primary progressive multiple sclerosis
D Marastoni, R Magliozzi, A Bolzan… - Neurology …, 2021 - AAN Enterprises
Background and Objectives To evaluate the extent of intrathecal inflammation in patients
with primary progressive MS (PPMS) at the time of diagnosis and to define markers and a …
with primary progressive MS (PPMS) at the time of diagnosis and to define markers and a …
Cell type-specific Nrf2 expression in multiple sclerosis lesions
Oxidative injury appears to play a major role in the propagation of demyelination and
neurodegeneration in multiple sclerosis (MS). It has been suggested that endogenous anti …
neurodegeneration in multiple sclerosis (MS). It has been suggested that endogenous anti …
Cerebellar lobule atrophy and disability in progressive MS
Objective To investigate global and lobular cerebellar volumetries in patients with
progressive multiple sclerosis (MS), testing the contribution of cerebellar lobular atrophy to …
progressive multiple sclerosis (MS), testing the contribution of cerebellar lobular atrophy to …
[HTML][HTML] The association between brain volume loss and disability in multiple sclerosis: A systematic review
Background Multiple sclerosis (MS) is a chronic, inflammatory, demyelinating, degenerative
disease of the central nervous system that affects approximately 2.8 million people …
disease of the central nervous system that affects approximately 2.8 million people …