[HTML][HTML] Mechanisms of ferroptosis regulating oxidative stress and energy metabolism in myocardial ischemia-reperfusion injury and a novel perspective of natural …

T Zhang, W Deng, Y Deng, Y Liu, S **ao, Y Luo… - Biomedicine & …, 2023 - Elsevier
Acute myocardial infarction remains the leading cause of death in humans. Timely
restoration of blood perfusion to ischemic myocardium remains the most effective strategy in …

Polyphenol-loaded nano-carriers for breast cancer therapy: a comprehensive review

AA Bhat, G Gupta, M Afzal, R Thapa, H Ali… - BioNanoScience, 2024 - Springer
Breast cancer remains a significant global health challenge, demanding innovative
therapeutic approaches. Polyphenols, a class of natural compounds widely distributed in …

[HTML][HTML] Recent strategies for cancer therapy: polymer nanoparticles carrying medicinally important phytochemicals and their cellular targets

M Yıldırım, M Sessevmez, S Poyraz, N Düzgüneş - Pharmaceutics, 2023 - mdpi.com
Cancer is a leading cause of death in the world today. In addition to the side effects of the
chemotherapeutic drugs used to treat cancer, the development of resistance to the drugs …

A comprehensive review of the PTEN/PI3K/Akt axis in multiple myeloma: from molecular interactions to potential therapeutic targets

M Alimohammadi, P Rahimzadeh, R Khorrami… - … -Research and Practice, 2024 - Elsevier
Phosphatase and tensin homolog (PTEN), phosphatidylinositol 3-kinase (PI3K), and protein
kinase B (Akt) signaling pathways contribute to the development of several cancers …

[HTML][HTML] Interaction of luteolin, naringenin, and their sulfate and glucuronide conjugates with human serum albumin, cytochrome P450 (CYP2C9, CYP2C19, and …

H Kaci, S Bodnárová, E Fliszár-Nyúl, B Lemli… - Biomedicine & …, 2023 - Elsevier
Luteolin and naringenin are flavonoids found in various foods/beverages and present in
certain dietary supplements. After a high intake of these flavonoids, their sulfate and …

Naringenin induces HepG2 cell apoptosis via ROS-mediated JAK-2/STAT-3 signaling pathways

M Zhang, J Lai, Q Wu, J Lai, J Su, B Zhu, Y Li - Molecules, 2023 - mdpi.com
Hepatocarcinoma is one of the most prevalent digestive system tumors worldwide and lacks
effective therapy. Recently, naringenin has been isolated from some citrus fruits, and its …

The effect of immunomodulatory properties of naringenin on the inhibition of inflammation and oxidative stress in autoimmune disease models: a systematic review …

M Alimohammadi, RN Mohammad, A Rahimi… - Inflammation …, 2022 - Springer
Background/objective Naringenin is a member of the flavonoid family that can perform many
biological processes to treat a wide range of inflammatory diseases and pathological …

Medicinal plants cultivated in Egypt with anticancer potential; a systematic review

IA Elshnoudy, AM Elkhouly, M Masoud… - Phytochemistry …, 2024 - Springer
The increase in cases of various cancers, the number of cancer patients, and the serious
side effects of current chemical treatments have encouraged researchers to discover novel …

Prediction model of clinical prognosis and immunotherapy efficacy of gastric cancer based on level of expression of cuproptosis-related genes

B Zhao, W Wu, L Liang, X Cai, Y Chen, W Tang - Heliyon, 2023 - cell.com
Background Gastric cancer is one of the most common malignancies in the world and ranks
fourth among cancer-related causes of death. Gastric adenocarcinoma is the most common …

Regulating miRNAs expression by resveratrol: novel insights based on molecular mechanism and strategies for cancer therapy

A Keshavarzmotamed, V Mousavi… - Current molecular …, 2024 - benthamdirect.com
Resveratrol, a polyphenolic phytoalexin found in a wide range of plants, including grapes,
berries, and peanuts, is an extensively researched phytochemical with unique …