The biosynthesis of L-phenylalanine-derived compounds by engineered microbes
M Qiu, J Jiang, W Jiang, W Zhang, Y Jiang, F **n… - Biotechnology …, 2024 - Elsevier
Abstract L-Phenylalanine (L-Phe) is an important aromatic amino acid, which has been
widely used in food, health care products, medicine and other fields. Based on the relatively …
widely used in food, health care products, medicine and other fields. Based on the relatively …
Research progress of ginseng in the treatment of gastrointestinal cancers
B Ni, X Song, B Shi, J Wang, Q Sun, X Wang… - Frontiers in …, 2022 - frontiersin.org
Cancer has become one of the major causes of human death. Several anticancer drugs are
available; howeve their use and efficacy are limited by the toxic side effects and drug …
available; howeve their use and efficacy are limited by the toxic side effects and drug …
Spectroscopic and molecular docking study of three kinds of cinnamic acid interaction with pepsin
S Zhu, T Wang, Y Zheng, Q Shi, Q Guo, J Zhu… - Spectrochimica Acta Part …, 2023 - Elsevier
In this work, under simulated physiological conditions (pH= 2.2, glycine hydrochloric acid
buffer solution), the interactions of cinnamic acid (CA), m-hydroxycinnamic acid (m-CA) and …
buffer solution), the interactions of cinnamic acid (CA), m-hydroxycinnamic acid (m-CA) and …
Design, synthesis, and evaluation of novel pleuromutilin aryl acrylate derivatives as promising broad-spectrum antibiotics especially for combatting multi-drug resistant …
M Li, J Li, J Li, J Zhang, Y Zhao, W Li, Y Zhang… - European Journal of …, 2023 - Elsevier
The emergence of drug-resistant strains presents a grave challenge for traditional
antibiotics, underscoring the exigency of exploring novel antibacterial drugs. To address …
antibiotics, underscoring the exigency of exploring novel antibacterial drugs. To address …
Design, synthesis, and characterization of cinnamic acid derivatives with two novel acrylohydrazones on HeLa and CHO-1 cancer cell lines: the experimental and …
Purpose To investigate the effect of derivatives of cinnamic acid on the proliferation of CHO-
1 and HeLa cell lines. Methods Three Acrylohydrazones (7–9) derived from cinnamic acid …
1 and HeLa cell lines. Methods Three Acrylohydrazones (7–9) derived from cinnamic acid …
HPLC Analysis and Molecular Docking Study of Myoporum serratum Seeds Extract with Its Bioactivity against Pathogenic Microorganisms and Cancer Cell Lines
Natural constituents have been utilized to avoid humanity from various diseases, such as
microbial infection and cancer, over several decades due to bioactive compounds …
microbial infection and cancer, over several decades due to bioactive compounds …
The anti‐breast cancer potential of indole/isatin hybrids
Breast cancer (BC) is one of the most prevalent malignancies and the major contributor to
cancer mortality in women globally, with a high degree of heterogeneity and a dismal …
cancer mortality in women globally, with a high degree of heterogeneity and a dismal …
[HTML][HTML] A Review of Cinnamic Acid's Skeleton Modification: Features for Antibacterial-Agent-Guided Derivatives
Antimicrobial resistance has emerged as a significant danger to global health, and the need
for more effective antimicrobial resistance (AMR) control has been highlighted. Cinnamic …
for more effective antimicrobial resistance (AMR) control has been highlighted. Cinnamic …
An In Vitro Antimicrobial, Anticancer and Antioxidant Activity of N–[(2–Arylmethylthio)phenylsulfonyl]cinnamamide Derivatives
A Bułakowska, J Sławiński, R Hałasa, A Hering… - Molecules, 2023 - mdpi.com
Cinnamic acid is a plant metabolite with antimicrobial, anticancer, and antioxidant
properties. Its synthetic derivatives are often more effective in vitro than parent compounds …
properties. Its synthetic derivatives are often more effective in vitro than parent compounds …
Design and synthesis of coumarin derivatives as cytotoxic agents through PI3K/AKT signaling pathway inhibition in HL60 and HepG2 cancer cells
In this study, a series of coumarin derivatives, either alone or as hybrids with cinnamic acid,
were synthesized and evaluated for their cytotoxicity against a panel of cancer cells using …
were synthesized and evaluated for their cytotoxicity against a panel of cancer cells using …