The Smad dependent TGF-β and BMP signaling pathway in bone remodeling and therapies
ML Zou, ZH Chen, YY Teng, SY Liu, Y Jia… - Frontiers in molecular …, 2021 - frontiersin.org
Bone remodeling is a continuous process that maintains the homeostasis of the skeletal
system, and it depends on the homeostasis between bone-forming osteoblasts and bone …
system, and it depends on the homeostasis between bone-forming osteoblasts and bone …
Neuroprotection by agmatine: Possible involvement of the gut microbiome?
P Saha, S Panda, A Holkar, R Vashishth… - Ageing Research …, 2023 - Elsevier
Agmatine, an endogenous polyamine derived from L-arginine, elicits tremendous
multimodal neuromodulant properties. Alterations in agmatinergic signalling are closely …
multimodal neuromodulant properties. Alterations in agmatinergic signalling are closely …
Agmatine modulation of gut-brain axis alleviates dysbiosis-induced depression-like behavior in rats
S Rahangdale, P Deshmukh, S Sammeta… - European Journal of …, 2024 - Elsevier
Depression is a global health concern affecting nearly 280 million individuals. It not only
imposes a significant burden on economies and healthcare systems but also manifests …
imposes a significant burden on economies and healthcare systems but also manifests …
Neuroprotective offerings by agmatine
NR Kotagale, BG Taksande, NN Inamdar - Neurotoxicology, 2019 - Elsevier
Agmatine, an endogenous polyamine in CNS, is derived from arginine by dearboxylation.
Like polyamines, agmatine has been studied for its neuroprotetive effects. At present, a large …
Like polyamines, agmatine has been studied for its neuroprotetive effects. At present, a large …
Astrocyte and oligodendrocyte responses from the subventricular zone after injury
J David-Bercholz, CT Kuo, B Deneen - Frontiers in Cellular …, 2021 - frontiersin.org
Under normal conditions, neural stem cells (NSCs or B cells) in the adult subventricular
zone (SVZ) give rise to amplifying neural progenitor cells (NPCs or C cells), which can …
zone (SVZ) give rise to amplifying neural progenitor cells (NPCs or C cells), which can …
The neuroprotective effects of agmatine on Parkinson's disease: Focus on oxidative stress, inflammation and molecular mechanisms
Agmatine (AGM), a naturally occurring polyamine derived from L-arginine, has shown
significant potential for neuroprotection in Parkinson's Disease (PD) due to its multifaceted …
significant potential for neuroprotection in Parkinson's Disease (PD) due to its multifaceted …
Therapeutic potential of agmatine for CNS disorders
Agmatine is a neuromodulator that regulates multiple neurotransmitters and signaling
pathways. Several studies have focused on elucidating the mechanisms underlying the …
pathways. Several studies have focused on elucidating the mechanisms underlying the …
[HTML][HTML] Evidence for safety of the dietary ingredient agmatine sulfate as assessed by mutagenicity and genotoxicity studies
VH Gilad, E Béres, A Vértesi, G Hirka, GM Gilad - Toxicology Reports, 2024 - Elsevier
Abstract Agmatine, 1-Amino-4-guanidinobutane, is a ubiquitous naturally occurring
molecule present in low amounts in a wide variety of foodstuff. Clinical trials have …
molecule present in low amounts in a wide variety of foodstuff. Clinical trials have …
Effects of primary microglia and astrocytes on neural stem cells in in vitro and in vivo models of ischemic stroke
SJ Wen, XM Zheng, LF Liu, NN Li, HA Mao… - Neural Regeneration …, 2021 - journals.lww.com
Transplantation of neural stem cells (NSCs) can protect neurons in animal stroke models;
however, their low rates of survival and neuronal differentiation limit their clinical application …
however, their low rates of survival and neuronal differentiation limit their clinical application …
Baicalin regulates stem cells as a creative point in the treatment of climacteric syndrome
It is widely acknowledged that the climacteric syndrome negatively affects women's quality of
life and leads to cerebral ischemic injury, osteoporosis and cardiovascular disease. One of …
life and leads to cerebral ischemic injury, osteoporosis and cardiovascular disease. One of …