The primary objective of this review article is to summarize how the neuroscience of brain
plasticity, exploiting new findings in fundamental, integrative and cognitive neuroscience, is …

A commonly observed neural correlate of working memory is firing that persists after the
triggering stimulus disappears. Substantial effort has been devoted to understanding the …

The psychological concepts of working memory and attention are widely used in the
cognitive and neuroscientific literatures. Perhaps because of the interdisciplinary appeal of …

In the idling brain, neuronal circuits transition between periods of sustained firing (UP state)
and quiescence (DOWN state), a pattern the mechanisms of which remain unclear. Here we …

Neural activity underlying working memory is not a local phenomenon but distributed across
multiple brain regions. To elucidate the circuit mechanism of such distributed activity, we …

Cortical networks spontaneously fluctuate between persistently active Up states and
quiescent Down states. The Up states are maintained by recurrent excitation within local …

Many brain functions depend on the ability of neural networks to temporally integrate
transient inputs to produce sustained discharges. This can occur through cell-autonomous …

Persistent elevated neuronal activity has been identified as the neuronal correlate of
working memory. It is generally assumed in the literature and in computational and …

What we see is fundamentally dependent on where we look. Despite this seemingly obvious
statement, many accounts of the neurobiology underpinning visual perception fail to …

During delayed oculomotor response tasks, neurons in the lateral intraparietal area (LIP)
and the frontal eye fields (FEF) exhibit persistent activity that reflects the active maintenance …