[HTML][HTML] Retinal remodeling in human retinitis pigmentosa

BW Jones, RL Pfeiffer, WD Ferrell, CB Watt… - Experimental eye …, 2016 - Elsevier
Retinitis Pigmentosa (RP) in the human is a progressive, currently irreversible neural
degenerative disease usually caused by gene defects that disrupt the function or …

Interpretation of OCT and OCTA images from a histological approach: Clinical and experimental implications

N Cuenca, I Ortuño-Lizarán, X Sanchez-Saez… - Progress in retinal and …, 2020 - Elsevier
Optical coherence tomography (OCT) and OCT angiography (OCTA) have been a
technological breakthrough in the diagnosis, treatment, and follow-up of many retinal …

Cellular characterization of OCT and outer retinal bands using specific immunohistochemistry markers and clinical implications

N Cuenca, I Ortuño-Lizarán, I Pinilla - Ophthalmology, 2018 - Elsevier
Purpose OCT has been a technological breakthrough in the diagnosis, treatment, and follow-
up of many ocular diseases, especially retinal and neuro-ophthalmologic pathologic …

Astrocytes and Müller cell alterations during retinal degeneration in a transgenic rat model of retinitis pigmentosa

L Fernández-Sánchez, P Lax, L Campello… - Frontiers in cellular …, 2015 - frontiersin.org
Purpose: Retinitis pigmentosa includes a group of progressive retinal degenerative
diseases that affect the structure and function of photoreceptors. Secondarily to the loss of …

Alternative methods to visual and radiographic examinations for approximal caries detection

N Abogazalah, M Ando - Journal of oral science, 2017 - jstage.jst.go.jp
A shift in caries prevalence from occlusal surfaces to approximal surfaces has been
demonstrated by epidemiological studies. Two recent meta-analyses evaluated the …

Phenotypic characterization of P23H and S334ter rhodopsin transgenic rat models of inherited retinal degeneration

MM LaVail, S Nishikawa, RH Steinberg… - Experimental eye …, 2018 - Elsevier
We produced 8 lines of transgenic (Tg) rats expressing one of two different rhodopsin
mutations in albino Sprague-Dawley (SD) rats. Three lines were generated with a proline to …

[HTML][HTML] Retinal ganglion cell death as a late remodeling effect of photoreceptor degeneration

D García-Ayuso, J Di Pierdomenico… - International journal of …, 2019 - mdpi.com
Inherited or acquired photoreceptor degenerations, one of the leading causes of irreversible
blindness in the world, are a group of retinal disorders that initially affect rods and cones …

Early events in retinal degeneration caused by rhodopsin mutation or pigment epithelium malfunction: differences and similarities

J Di Pierdomenico, D García-Ayuso, I Pinilla… - Frontiers in …, 2017 - frontiersin.org
To study the course of photoreceptor cell death and macro and microglial reactivity in two rat
models of retinal degeneration with different etiologies. Retinas from P23H-1 (rhodopsin …

[HTML][HTML] Gradual increase in environmental light intensity induces oxidative stress and inflammation and accelerates retinal neurodegeneration

O Kutsyr, X Sánchez-Sáez… - … & Visual Science, 2020 - tvst.arvojournals.org
Purpose: Retinitis pigmentosa (RP) is a blinding neurodegenerative disease of the retina
that can be affected by many factors. The present study aimed to analyze the effect of …

[HTML][HTML] Controlled delivery of tauroursodeoxycholic acid from biodegradable microspheres slows retinal degeneration and vision loss in P23H rats

L Fernandez-Sanchez, I Bravo-Osuna, P Lax… - PLoS …, 2017 - journals.plos.org
Successful drug therapies for treating ocular diseases require effective concentrations of
neuroprotective compounds maintained over time at the site of action. The purpose of this …