[HTML][HTML] Pleiotropic effects of BDNF on the cerebellum and hippocampus: Implications for neurodevelopmental disorders

S Camuso, P La Rosa, MT Fiorenza, S Canterini - Neurobiology of disease, 2022 - Elsevier
Brain-derived neurotrophic factor (BDNF) is one of the most studied neurotrophins in the
mammalian brain, essential not only to the development of the central nervous system but …

Physiology of the cerebellum

E D'Angelo - Handbook of clinical neurology, 2018 - Elsevier
The cerebellum is a central brain structure deeply integrated into major loops with the
cerebral cortex, brainstem, and spinal cord. The cerebellum shows a complex regional …

Cerebellum lecture: the cerebellar nuclei—core of the cerebellum

JM Kebschull, F Casoni, GG Consalez, D Goldowitz… - The Cerebellum, 2024 - Springer
The cerebellum is a key player in many brain functions and a major topic of neuroscience
research. However, the cerebellar nuclei (CN), the main output structures of the cerebellum …

Variations on the theme: focus on cerebellum and emotional processing

C Ciapponi, Y Li, DA Osorio Becerra… - Frontiers in Systems …, 2023 - frontiersin.org
The cerebellum operates exploiting a complex modular organization and a unified
computational algorithm adapted to different behavioral contexts. Recent observations …

Modeling the cerebellar microcircuit: new strategies for a long-standing issue

E D'Angelo, A Antonietti, S Casali… - Frontiers in cellular …, 2016 - frontiersin.org
The cerebellar microcircuit has been the work bench for theoretical and computational
modeling since the beginning of neuroscientific research. The regular neural architecture of …

Model simulations unveil the structure-function-dynamics relationship of the cerebellar cortical microcircuit

R De Schepper, A Geminiani, S Masoli… - Communications …, 2022 - nature.com
The cerebellar network is renowned for its regular architecture that has inspired foundational
computational theories. However, the relationship between circuit structure, function and …

α6-Containing GABAA receptors: functional roles and therapeutic potentials

W Sieghart, LC Chiou, M Ernst, J Fabjan… - Pharmacological …, 2022 - Elsevier
GABA A receptors containing the α6 subunit are highly expressed in cerebellar granule cells
and less abundantly in many other neuronal and peripheral tissues. Here, we for the first …

Diverse neuron properties and complex network dynamics in the cerebellar cortical inhibitory circuit

F Prestori, L Mapelli, E D'Angelo - Frontiers in molecular neuroscience, 2019 - frontiersin.org
Neuronal inhibition can be defined as a spatiotemporal restriction or suppression of local
microcircuit activity. The importance of inhibition relies in its fundamental role in sha** …

Expansion microscopy: scalable and convenient super-resolution microscopy

PW Tillberg, F Chen - Annual Review of Cell and …, 2019 - annualreviews.org
Expansion microscopy (ExM) is a physical form of magnification that increases the effective
resolving power of any microscope. Here, we describe the fundamental principles of ExM, as …

[HTML][HTML] Cerebellar α6GABAA receptors as a therapeutic target for essential tremor: proof-of-concept study with ethanol and pyrazoloquinolinones

YH Huang, MT Lee, HY Hsueh, DE Knutson, J Cook… - …, 2023 - Elsevier
Ethanol has been shown to suppress essential tremor (ET) in patients at low-to-moderate
doses, but its mechanism (s) of action remain unknown. One of the ET hypotheses attributes …