Alteration of gut microbiota in inflammatory bowel disease (IBD): cause or consequence? IBD treatment targeting the gut microbiome

I Khan, N Ullah, L Zha, Y Bai, A Khan, T Zhao, T Che… - Pathogens, 2019 - mdpi.com
Inflammatory bowel disease (IBD) is a chronic complex inflammatory gut pathological
condition, examples of which include Crohn's disease (CD) and ulcerative colitis (UC) …

Host–microbiota maladaptation in colorectal cancer

A Janney, F Powrie, EH Mann - Nature, 2020 - nature.com
Colorectal cancer (CRC) is a heterogeneous disease of the intestinal epithelium that is
characterized by the accumulation of mutations and a dysregulated immune response. Up to …

The intestinal microbiota in colorectal cancer

H Tilg, TE Adolph, RR Gerner, AR Moschen - Cancer cell, 2018 - cell.com
Experimental evidence from the past years highlights a key role for the intestinal microbiota
in inflammatory and malignant gastrointestinal diseases. Diet exhibits a strong impact on …

Macrophage IL-10 blocks CD8+ T cell-dependent responses to chemotherapy by suppressing IL-12 expression in intratumoral dendritic cells

B Ruffell, D Chang-Strachan, V Chan, A Rosenbusch… - Cancer cell, 2014 - cell.com
Blockade of colony-stimulating factor-1 (CSF-1) limits macrophage infiltration and improves
response of mammary carcinomas to chemotherapy. Herein we identify interleukin (IL)-10 …

A new dawn for eosinophils in the tumour microenvironment

S Grisaru-Tal, M Itan, AD Klion, A Munitz - Nature Reviews Cancer, 2020 - nature.com
Eosinophils are evolutionarily conserved, pleotropic cells that display key effector functions
in allergic diseases, such as asthma. Nonetheless, eosinophils infiltrate multiple tumours …

Gut microbiota in cancer immune response and immunotherapy

CB Zhou, YL Zhou, JY Fang - Trends in cancer, 2021 - cell.com
The gastrointestinal tract (GIT) is the largest immune organ and maintains systemic immune
homeostasis in the presence of bacterial challenge. Immune elimination and immune …

Performance and microbial community analysis of a novel DEAMOX based on partial-denitrification and anammox treating ammonia and nitrate wastewaters

R Du, S Cao, B Li, M Niu, S Wang, Y Peng - Water Research, 2017 - Elsevier
In this study, a novel DEAMOX (DEnitrifying AMmonium O**dation) process coupling
anammox with partial-denitrification generated nitrite (NO 2−-N) from nitrate (NO 3−-N) was …

Microbial network disturbances in relapsing refractory Crohn's disease

B Yilmaz, P Juillerat, O Øyås, C Ramon, FD Bravo… - Nature medicine, 2019 - nature.com
Inflammatory bowel diseases (IBD) can be broadly divided into Crohn's disease (CD) and
ulcerative colitis (UC) from their clinical phenotypes. Over 150 host susceptibility genes have …

Quantify the contribution of anammox for enhanced nitrogen removal through metagenomic analysis and mass balance in an anoxic moving bed biofilm reactor

J Li, Y Peng, L Zhang, J Liu, X Wang, R Gao, L Pang… - Water Research, 2019 - Elsevier
In this study, enhanced nitrogen removal through in situ enrichment of anammox bacteria
was successfully obtained in a full-scale municipal wastewater treatment plant (WWTP). The …

From hybrid process to pure biofilm anammox process: Suspended sludge biomass management contributing to high-level anammox enrichment in biofilms

Q Zhao, J Li, L Deng, T Jia, Y Zhao, X Li, Y Peng - Water Research, 2023 - Elsevier
The application of mainstream anammox is highly desirable for municipal wastewater
treatment. However, enrichment of anammox bacteria (AnAOB) is challenging, particularly …