Current approaches of preservation of cells during (freeze-) drying

U Rockinger, M Funk, G Winter - Journal of Pharmaceutical Sciences, 2021 - Elsevier
The widespread application of therapeutic cells requires a successful stabilization of cells for
the duration of transport and storage. Cryopreservation is currently considered the gold …

The chemistry of lyophilized blood products

J Fernandez-Moure, N Maisha, EB Lavik… - Bioconjugate …, 2018 - ACS Publications
With the development of new biologics and bioconjugates, storage and preservation have
become more critical than ever before. Lyophilization is a method of cell and protein …

Freeze-drying of mononuclear cells derived from umbilical cord blood followed by colony formation

D Natan, A Nagler, A Arav - PloS one, 2009 - journals.plos.org
Background We recently showed that freeze-dried cells stored for 3 years at room
temperature can direct embryonic development following cloning. However, viability, as …

[CARTE][B] Advances in biopreservation

JG Baust, JM Baust - 2006 - taylorfrancis.com
Moving rapidly from science fiction to science fact, cryopreservation is an integral part of
many research, development, and production processes in industry and academia. The …

Improved preservation of human red blood cells by lyophilization

Y Han, GB Quan, XZ Liu, EP Ma, A Liu, P **, W Cao - Cryobiology, 2005 - Elsevier
The lyophilization of human red blood cells has important implications for blood transfusion
in clinical medicine. In this study, sugars, human serum albumin, polyvinylpyrrolidone, and …

Phospholipid vesicles increase the survival of freeze-dried human red blood cells

A Kheirolomoom, GR Satpathy, Z Török, M Banerjee… - Cryobiology, 2005 - Elsevier
In a previous report [Z. Török, G. Satpathy, M. Banerjee, R. Bali, E. Little, R. Novaes, H. Van
Ly, D. Dwyre, A. Kheirolomoom, F. Tablin, JH Crowe, NM Tsvetkova, Preservation of …

Advances in Targeting Drug Biological Carriers for Enhancing Tumor Therapy Efficacy

D **a, J Li, L Feng, Z Gao, J Liu… - Macromolecular …, 2023 - Wiley Online Library
Chemotherapy drugs continue to be the main component of oncology treatment research
and have been proven to be the main treatment modality in tumor therapy. However, the …

Freeze‐Dried Mesenchymal Stem Cells: From Bench to Bedside. Review

T Paresishvili, Z Kakabadze - Advanced Biology, 2024 - Wiley Online Library
This review describes the freeze‐dried mesenchymal stem cells (MSCs) and their ability to
restore damaged tissues and organs. An analysis of the literature shows that after the …

Freeze drying of red blood cells: the use of directional freezing and a new radio frequency lyophilization device

A Arav, D Natan - Biopreservation and Biobanking, 2012 - liebertpub.com
Red blood cell (RBC) units are administered routinely into patients expressing a wide range
of acute and chronic conditions (eg, anemia, traumatic bleeding, chronic diseases, and …

Mammalian cell desiccation: facing the challenges

T Kanias, JP Acker - Cell preservation technology, 2006 - liebertpub.com
The current techniques for the biopreservation of mammalian cells, such as red blood cells,
human platelets, sperm cells, and stem cells, rely on hypothermic storage, which has many …