The intrinsic cardiac nervous system and its role in cardiac pacemaking and conduction

L Fedele, T Brand - Journal of cardiovascular development and disease, 2020 - mdpi.com
The cardiac autonomic nervous system (CANS) plays a key role for the regulation of cardiac
activity with its dysregulation being involved in various heart diseases, such as cardiac …

Guidelines for assessment of cardiac electrophysiology and arrhythmias in small animals

CM Ripplinger, AV Glukhov, MW Kay… - American Journal …, 2022 - journals.physiology.org
Cardiac arrhythmias are a major cause of morbidity and mortality worldwide. Although
recent advances in cell-based models, including human-induced pluripotent stem cell …

Lifelong Endurance Exercise as a Countermeasure Against Age-Related Decline: Physiological Overview and Insights from Masters Athletes

PL Valenzuela, NA Maffiuletti, MJ Joyner, A Lucia… - Sports Medicine, 2020 - Springer
Maximum oxygen consumption (̇ VO _ 2 max V˙ O 2 max) is not only an indicator of
endurance performance, but also a strong predictor of cardiovascular disease and mortality …

Calcium signaling pathways: key pathways in the regulation of obesity

Z Song, Y Wang, F Zhang, F Yao, C Sun - International journal of …, 2019 - mdpi.com
Nowadays, high epidemic obesity-triggered hypertension and diabetes seriously damage
social public health. There is now a general consensus that the body's fat content exceeding …

Chronic nicotine exposure is associated with electrophysiological and sympathetic remodeling in the intact rabbit heart

A Guevara, CER Smith, JL Caldwell… - American Journal …, 2024 - journals.physiology.org
Nicotine is the primary addictive component of tobacco products. Through its actions on the
heart and autonomic nervous system, nicotine exposure is associated with …

[HTML][HTML] Ventricular arrhythmias in acute myocardial ischaemia—Focus on the ageing and sex

M Oknińska, M Mączewski, U Mackiewicz - Ageing Research Reviews, 2022 - Elsevier
Annually, approximately 17 million people die from cardiovascular diseases worldwide, half
of them suddenly. The most common direct cause of sudden cardiac death is ventricular …

Adrenergic supersensitivity and impaired neural control of cardiac electrophysiology following regional cardiac sympathetic nerve loss

S Tapa, L Wang, SD Francis Stuart, Z Wang, Y Jiang… - Scientific reports, 2020 - nature.com
Myocardial infarction (MI) can result in sympathetic nerve loss in the infarct region. However,
the contribution of hypo-innervation to electrophysiological remodeling, independent from MI …

Age-related changes in cardiac autonomic modulation and heart rate variability in mice

C Piantoni, L Carnevali, D Molla, A Barbuti… - Frontiers in …, 2021 - frontiersin.org
Objective The aim of this study was to assess age-related changes in cardiac autonomic
modulation and heart rate variability (HRV) and their association with spontaneous and …

Incorrectly corrected? QT interval analysis in rats and mice

W Mulla, M Murninkas, O Levi, Y Etzion - Frontiers in Physiology, 2022 - frontiersin.org
QT interval, a surrogate measure for ventricular action potential duration (APD) in the
surface ECG, is widely used to identify cardiac abnormalities and drug safety. In humans …

Cardiac sympathetic nerve transdifferentiation reduces action potential heterogeneity after myocardial infarction

L Wang, A Olivas, SD Francis Stuart… - American Journal …, 2020 - journals.physiology.org
Cardiac sympathetic nerves undergo cholinergic transdifferentiation following reperfused
myocardial infarction (MI), whereby the sympathetic nerves release both norepinephrine …