The treatment of individual patients in cardiology practice increasingly relies on advanced
imaging, genetic screening and devices. As the amount of imaging and other diagnostic …

Over the last decade, the state‐of‐the‐art in cardiac computational modelling has
progressed rapidly. The electrophysiological function of the heart can now be simulated with …

Bradyarrhythmias are an important cause of mortality in heart failure and previous studies
indicate a mechanistic role for electrical remodelling of the key pacemaking ion channel …

As specialized compartments of the heart, the atria feature unique mechanical and structural
properties that differ considerably from those of the ventricular myocardium. Beyond their …

Aims Left-ventricular (LV) conduction disturbances are common in heart-failure patients and
a left bundle-branch block (LBBB) electrocardiogram (ECG) type is often seen. The precise …

Computational models have become a fundamental tool in cardiac research. Models are
evolving to cover multiple scales and physical mechanisms. They are moving towards …

Introduction The extent of left atrial (LA) adverse remodeling as a cardiac disease marker
has become increasingly important. In patients with atrial fibrillation (AF), atrial remodeling …

Cardiac resynchronization therapy (CRT) is an effective treatment for heart failure (HF)
patients with an electrical substrate pathology causing ventricular dyssynchrony. However …

Cardiac resynchronization therapy (CRT) is an established treatment for left bundle branch
block (LBBB) resulting in mechanical dyssynchrony. Approximately 1/3 of patients with CRT …

Patient-specific modeling of ventricular electrophysiology requires an interpolated
reconstruction of the 3-dimensional (3D) geometry of the patient ventricles from the low …