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Microbiota succession throughout life from the cradle to the grave
Associations between age and the human microbiota are robust and reproducible. The
microbial composition at several body sites can predict human chronological age relatively …
microbial composition at several body sites can predict human chronological age relatively …
The human virome: assembly, composition and host interactions
The human body hosts vast microbial communities, termed the microbiome. Less well
known is the fact that the human body also hosts vast numbers of different viruses …
known is the fact that the human body also hosts vast numbers of different viruses …
The gut ileal mucosal virome is disturbed in patients with Crohn's disease and exacerbates intestinal inflammation in mice
Z Cao, D Fan, Y Sun, Z Huang, Y Li, R Su… - Nature …, 2024 - nature.com
Gut bacteriome dysbiosis is known to be implicated in the pathogenesis of inflammatory
bowel disease (IBD). Crohn's disease (CD) is an IBD subtype with extensive mucosal …
bowel disease (IBD). Crohn's disease (CD) is an IBD subtype with extensive mucosal …
Genomic diversity and ecology of human-associated Akkermansia species in the gut microbiome revealed by extensive metagenomic assembly
Background Akkermansia muciniphila is a human gut microbe with a key role in the
physiology of the intestinal mucus layer and reported associations with decreased body …
physiology of the intestinal mucus layer and reported associations with decreased body …
Human enteric viruses autonomously shape inflammatory bowel disease phenotype through divergent innate immunomodulation
F Adiliaghdam, H Amatullah, S Digumarthi… - Science …, 2022 - science.org
Altered enteric microorganisms in concert with host genetics shape inflammatory bowel
disease (IBD) phenotypes. However, insight is limited to bacteria and fungi. We found that …
disease (IBD) phenotypes. However, insight is limited to bacteria and fungi. We found that …
Phage-microbe dynamics after sterile faecal filtrate transplantation in individuals with metabolic syndrome: a double-blind, randomised, placebo-controlled clinical trial …
Bacteriophages (phages) are bacterial viruses that have been shown to shape microbial
communities. Previous studies have shown that faecal virome transplantation can decrease …
communities. Previous studies have shown that faecal virome transplantation can decrease …
The human virome: viral metagenomics, relations with human diseases, and therapeutic applications
The human body is colonized by a wide range of microorganisms. The field of viromics has
expanded since the first reports on the detection of viruses via metagenomic sequencing in …
expanded since the first reports on the detection of viruses via metagenomic sequencing in …
Gut virome in inflammatory bowel disease and beyond
Objective The gut virome is a dense community of viruses inhabiting the gastrointestinal tract
and an integral part of the microbiota. The virome coexists with the other components of the …
and an integral part of the microbiota. The virome coexists with the other components of the …
Fecal virus-like particles are sufficient to reduce necrotizing enterocolitis
SM Offersen, X Mao, MR Spiegelhauer, F Larsen… - Gut …, 2024 - Taylor & Francis
Fecal filtrate transfer (FFT) is emerging as a safer alternative to traditional fecal microbiota
transplantation (FMT)–particularly in the context of necrotizing enterocolitis (NEC), a severe …
transplantation (FMT)–particularly in the context of necrotizing enterocolitis (NEC), a severe …
Gut virome-wide association analysis identifies cross-population viral signatures for inflammatory bowel disease
Background The gut virome has been implicated in inflammatory bowel disease (IBD), yet a
full understanding of the gut virome in IBD patients, especially across diverse geographic …
full understanding of the gut virome in IBD patients, especially across diverse geographic …