Three-dimensional identification of microvascular pathology and neurovascular inflammation in severe white matter hyperintensity: a case report

G Solé-Guardia, M Luijten, B Geenen… - Scientific Reports, 2024 - nature.com
White matter hyperintensities (WMH) are the most prevalent markers of cerebral small vessel
disease (SVD), which is the major vascular risk factor for dementia. Microvascular pathology …

Flusilazole induced developmental toxicity, neurotoxicity, and cardiovascular toxicity via apoptosis and oxidative stress in zebrafish

H Lee, G An, W Lim, G Song - … and Physiology Part C: Toxicology & …, 2024 - Elsevier
Flusilazole is a well-known triazole fungicide applied to various crops and fruits worldwide.
Flusilazole residues are frequently detected in the environment, and many researchers have …

[HTML][HTML] IL-1β disrupts the initiation of blood-brain barrier development by inhibiting endothelial Wnt/β-catenin signaling

AR Fetsko, DJ Sebo, LB Budzynski, A Scharbarth… - Iscience, 2024 - cell.com
During neuroinflammation, the proinflammatory cytokine interleukin-1β (IL-1β) impacts blood-
brain barrier (BBB) function by disrupting brain endothelial tight junctions, promoting …

Therapeutic targeting of vascular malformation in a zebrafish model of hereditary haemorrhagic telangiectasia

RO Snodgrass, K Govindpani, K Plant… - Disease Models & …, 2023 - journals.biologists.com
Hereditary haemorrhagic telangiectasia (HHT) causes arteriovenous malformations (AVMs)
in multiple organs to cause bleeding, neurological and other complications. HHT is caused …

Quantitative characterization of zebrafish development based on multiple classifications using Mueller matrix OCT

K Li, B Liu, Z Wang, Y Li, H Li, S Wu… - Biomedical Optics Express, 2023 - opg.optica.org
Organ development analysis plays an important role in assessing an individual's growth
health. In this study, we present a non-invasive method for the quantitative characterization …

Development and repair of blood vessels in the zebrafish spinal cord

A Ribeiro, M Rebocho da Costa… - Open …, 2023 - royalsocietypublishing.org
The vascular system is inefficiently repaired after spinal cord injury (SCI) in mammals,
resulting in secondary tissue damage and immune deregulation that contribute to the limited …

Vessel Metrics: A software tool for automated analysis of vascular structure in confocal imaging

SD McGarry, C Adjekukor, S Ahuja… - Microvascular …, 2024 - Elsevier
Images contain a wealth of information that is often under analyzed in biological studies.
Developmental models of vascular disease are a powerful way to quantify developmentally …

Q-VAT: Quantitative Vascular Analysis Tool

B Callewaert, W Gsell, U Himmelreich… - Frontiers in …, 2023 - frontiersin.org
As our imaging capability increase, so does our need for appropriate image quantification
tools. Quantitative Vascular Analysis Tool (Q-VAT) is an open-source software, written for Fiji …

Three-dimensional cerebral vasculature topological parameter extraction of transgenic zebrafish embryos with a filling-enhancement deep learning network

C Chen, YJ Tang, Y Tan, LB Wang, H Li - Biomedical Optics Express, 2023 - opg.optica.org
Quantitative analysis of zebrafish cerebral vasculature is essential for the study of vascular
development and disease. We developed a method to accurately extract the cerebral …

IL-1β disrupts blood-brain barrier development by inhibiting endothelial Wnt/β-catenin signaling

AR Fetsko, DJ Sebo, LB Budzynski, A Scharbarth… - …, 2024 - pmc.ncbi.nlm.nih.gov
During neuroinflammation, the proinflammatory cytokine Interleukin-1β (IL-1β) impacts blood-
brain barrier (BBB) function by disrupting brain endothelial tight junctions, promoting …