The Helicobacter pylori cag type IV secretion system

TL Cover, DB Lacy, MD Ohi - Trends in microbiology, 2020‏ - cell.com
Colonization of the human stomach with Helicobacter pylori strains containing the cag
pathogenicity island is a risk factor for development of gastric cancer. The cag pathogenicity …

[HTML][HTML] Influence of the microbiome metagenomics and epigenomics on gastric cancer

P Mathebela, BP Damane, TV Mulaudzi… - International Journal of …, 2022‏ - mdpi.com
Gastric cancer (GC) is one of the major causes of cancer deaths worldwide. The disease is
seldomly detected early and this limits treatment options. Because of its heterogeneous and …

Angiopep-2-functionalized nanoparticles enhance transport of protein drugs across intestinal epithelia by self-regulation of targeted receptors

X Liu, R Wu, Y Li, L Wang, R Zhou, L Li, Y **ang… - Biomaterials …, 2021‏ - pubs.rsc.org
Ligand-modified nanoparticles (NPs) have been widely used in oral drug delivery systems to
promote endocytosis on intestinal epithelia. However, their transcytosis across the intestinal …

Epigenetic Regulation of Tumor Suppressors by Helicobacter pylori Enhances EBV-Induced Proliferation of Gastric Epithelial Cells

S Pandey, HC Jha, SK Shukla, MK Shirley… - MBio, 2018‏ - journals.asm.org
ABSTRACT Helicobacter pylori and Epstein-Barr virus (EBV) are two well-known
contributors to cancer and can establish lifelong persistent infection in the host. This leads to …

Cellular evasion strategies of Helicobacter pylori in regulating its intracellular fate

WY Sit, YA Chen, YL Chen, CH Lai… - Seminars in cell & …, 2020‏ - Elsevier
Helicobacter pylori colonizes human stomach mucosa and its infection causes
gastrointestinal diseases with variable severity. Bacterial infection stimulates autophagy …

Functional and biochemical characterisation of remote homologues of type IV pili proteins PilN and PilO in Helicobacter pylori

SQ Bonny, X Zhou, MF Khan, MM Rahman, Y **n… - IUBMB …, 2024‏ - Wiley Online Library
Helicobacter pylori encodes homologues of PilM, PilN and PilO from bacteria with Type IV
pili, where these proteins form a pilus alignment complex. Inactivation of pilO changes H …

The Helicobacter pylori infection alters the intercellular junctions on the pancreas of gerbils (Meriones unguiculatus)

EG Hurtado-Monzón, P Valencia-Mayoral… - World Journal of …, 2024‏ - Springer
Helicobacter pylori is a common resident in the stomach of at least half of the world's
population and recent evidence suggest its emergence in other organs such as the …

Pal power: Demonstration of the functional association of the Helicobacter pylori flagellar motor with peptidoglycan-associated lipoprotein (Pal) and its preliminary …

X Zhou, MM Rahman, SQ Bonny, Y **n… - BioScience …, 2023‏ - jstage.jst.go.jp
The bacterial flagellar motor is a molecular nanomachine, the assembly and regulation of
which requires many accessory proteins. Their identity, structure and function are often …

Inhibitory and injury-protection effects of O-glycan on gastric epithelial cells infected with Helicobacter pylori

Y Chen, Z Tang, L Fu, R Liu, L Yang… - Infection and …, 2022‏ - journals.asm.org
Helicobacter pylori (H. pylori) is an important pathogen that can cause gastric cancer.
Multiple adhesion molecules mediated H. pylori adherence to cells is the initial step in the …

Biochemical characterization of paralyzed flagellum proteins A (PflA) and B (PflB) from Helicobacter pylori flagellar motor

X Zhou, MF Khan, Y **n, KL Chan… - Bioscience …, 2024‏ - portlandpress.com
Motility by means of flagella plays an important role in the persistent colonization of
Helicobacter pylori in the human stomach. The H. pylori flagellar motor has a complex …