An introduction to the endogenous cannabinoid system
The endocannabinoid system (ECS) is a widespread neuromodulatory system that plays
important roles in central nervous system development, synaptic plasticity, and the response …
important roles in central nervous system development, synaptic plasticity, and the response …
The endocannabinoid system in guarding against fear, anxiety and stress
The endocannabinoid (eCB) system has emerged as a central integrator linking the
perception of external and internal stimuli to distinct neurophysiological and behavioural …
perception of external and internal stimuli to distinct neurophysiological and behavioural …
Endocannabinoid signaling and synaptic function
Endocannabinoids are key modulators of synaptic function. By activating cannabinoid
receptors expressed in the central nervous system, these lipid messengers can regulate …
receptors expressed in the central nervous system, these lipid messengers can regulate …
Role of metabotropic glutamate receptors in neurological disorders
R Crupi, D Impellizzeri, S Cuzzocrea - Frontiers in molecular …, 2019 - frontiersin.org
Glutamate is a fundamental excitatory neurotransmitter in the mammalian central nervous
system (CNS), playing key roles in memory, neuronal development, and synaptic plasticity …
system (CNS), playing key roles in memory, neuronal development, and synaptic plasticity …
Multiple functions of endocannabinoid signaling in the brain
I Katona, TF Freund - Annual review of neuroscience, 2012 - annualreviews.org
Despite being regarded as a hippie science for decades, cannabinoid research has finally
found its well-deserved position in mainstream neuroscience. A series of groundbreaking …
found its well-deserved position in mainstream neuroscience. A series of groundbreaking …
[HTML][HTML] Endocannabinoid-mediated control of synaptic transmission
M Kano, T Ohno-Shosaku… - Physiological …, 2009 - journals.physiology.org
The discovery of cannabinoid receptors and subsequent identification of their endogenous
ligands (endocannabinoids) in early 1990s have greatly accelerated research on …
ligands (endocannabinoids) in early 1990s have greatly accelerated research on …
[HTML][HTML] 2-Arachidonoylglycerol: A signaling lipid with manifold actions in the brain
Arachidonoylglycerol (2-AG) is a signaling lipid in the central nervous system that is a key
regulator of neurotransmitter release. 2-AG is an endocannabinoid that activates the …
regulator of neurotransmitter release. 2-AG is an endocannabinoid that activates the …
Programming of neural cells by (endo) cannabinoids: from physiological rules to emerging therapies
Among the many signalling lipids, endocannabinoids are increasingly recognized for their
important roles in neuronal and glial development. Recent experimental evidence suggests …
important roles in neuronal and glial development. Recent experimental evidence suggests …
Cannabis-associated psychosis: Neural substrate and clinical impact
Prospective epidemiological studies have consistently demonstrated that cannabis use is
associated with an increased subsequent risk of both psychotic symptoms and …
associated with an increased subsequent risk of both psychotic symptoms and …
Endocannabinoid signaling as a synaptic circuit breaker in neurological disease
I Katona, TF Freund - Nature medicine, 2008 - nature.com
Cannabis sativa is one of the oldest herbal plants in the history of medicine. It was used in
various therapeutic applications from pain to epilepsy, but its psychotropic effect has …
various therapeutic applications from pain to epilepsy, but its psychotropic effect has …