Non-invasive delivery strategies for biologics
Biologics now constitute a significant element of available medical treatments. Owing to their
clinical and commercial success, biologics are a rapidly growing class and have become a …
clinical and commercial success, biologics are a rapidly growing class and have become a …
Advances in the application of electrospun drug-loaded nanofibers in the treatment of oral ulcers
Y Zhou, M Wang, C Yan, H Liu, DG Yu - Biomolecules, 2022 - mdpi.com
Oral ulcers affect oral and systemic health and have high prevalence in the population.
There are significant individual differences in the etiology and extent of the disease among …
There are significant individual differences in the etiology and extent of the disease among …
Peptide chemistry toolbox–Transforming natural peptides into peptide therapeutics
M Erak, K Bellmann-Sickert, S Els-Heindl… - Bioorganic & medicinal …, 2018 - Elsevier
The development of solid phase peptide synthesis has released tremendous opportunities
for using synthetic peptides in medicinal applications. In the last decades, peptide …
for using synthetic peptides in medicinal applications. In the last decades, peptide …
Strategic approaches to improvise peptide drugs as next generation therapeutics
In recent years, the occurrence of a wide variety of drug-resistant diseases has led to an
increase in interest in alternate therapies. Peptide-based drugs as an alternate therapy hold …
increase in interest in alternate therapies. Peptide-based drugs as an alternate therapy hold …
A slippery slope: On the origin, role and physiology of mucus
F Taherali, F Varum, AW Basit - Advanced drug delivery reviews, 2018 - Elsevier
The mucosa of the gastrointestinal tract, eyes, nose, lungs, cervix and vagina is lined by
epithelium interspersed with mucus-secreting goblet cells, all of which contribute to their …
epithelium interspersed with mucus-secreting goblet cells, all of which contribute to their …
An updated overview of the emerging role of patch and film-based buccal delivery systems
Buccal mucosal membrane offers an attractive drug-delivery route to enhance both systemic
and local therapy. This review discusses the benefits and drawbacks of buccal drug delivery …
and local therapy. This review discusses the benefits and drawbacks of buccal drug delivery …
Novel and revisited approaches in nanoparticle systems for buccal drug delivery
AS Macedo, PM Castro, L Roque, NG Thomé… - Journal of Controlled …, 2020 - Elsevier
The buccal route is considered patient friendly due to its non-invasive nature and ease of
administration. Such delivery route has been used as an alternative for the delivery of drugs …
administration. Such delivery route has been used as an alternative for the delivery of drugs …
Challenges and future prospects for the delivery of biologics: oral mucosal, pulmonary, and transdermal routes
Biologic products are large molecules such as proteins, peptides, nucleic acids, etc., which
have already produced many new drugs for clinical use in the last decades. Due to the …
have already produced many new drugs for clinical use in the last decades. Due to the …
An overview of polymeric dosage forms in buccal drug delivery: State of art, design of formulations and their in vivo performance evaluation
Owing to the ease of the administration, the oral cavity is an attractive site for the delivery of
drugs. The main difficulty for administration via the buccal route is an effective physiological …
drugs. The main difficulty for administration via the buccal route is an effective physiological …
Buccal delivery of small molecules and biologics: of mucoadhesive polymers, films, and nanoparticles–an update
VV Nair, P Cabrera, C Ramírez-Lecaros… - International Journal of …, 2023 - Elsevier
Buccal delivery of small and large molecules is an attractive route of administration that has
been studied extensively over the past few decades. This route bypasses first-pass …
been studied extensively over the past few decades. This route bypasses first-pass …