Natural product compounds have recently attracted significant attention from the scientific
community for their potent effects against inflammation-driven diseases, including cancer. A …

Transglutaminases (TGs) are multifunctional proteins having enzymatic and scaffolding
functions that participate in regulation of cell fate in a wide range of cellular systems and are …

Although links between cancer and inflammation were firstly proposed in the nineteenth
century, the molecular mechanism has not yet been clearly understood. Epidemiological …

Tumor progression involves the ability of cancer cells to communicate with each other and
with neighboring normal cells in their microenvironment. Microvesicles (MV) derived from …

Autophagy, a lysosomal degradation pathway for cellular constituents and organelles, is an
adaptive and essential process required for cellular homeostasis. Although autophagy …

Importance of the field: Nuclear factor kappa B (NF-κB) is activated by a variety of cancer-
promoting agents. The reciprocal activation between NF-κB and inflammatory cytokines …

NF-κB, a transcription factor first discovered in 1986, is now known to be closely connected
to the process of tumorogenesis based on a multiplicity of evidence.(1) NF-κB is activated in …

Terpenes are compounds that include monoterpenes, sesquiterpenes, diterpenes, and
terpenes, where isoprene is the basic structural unit of multiple oxygenated hydrocarbons …

Nuclear factor-κB (NF-κB) is a proinflammatory transcription factor that has emerged as an
important player in the development and progression of malignant cancers. NF-κB targets …

Transglutaminase 2 (TG2 or tissue transglutaminase) is a highly complex multifunctional
protein that acts as transglutaminase, GTPase/ATPase, protein disulfide isomerase, and …