Peripheral nerve injuries commonly occur due to trauma, like a traffic accident. Peripheral
nerves get severed, causing motor neuron death and potential muscle atrophy. The current …

Many neurodegenerative diseases have been associated with defects in primary cilia, which
are cellular organelles involved in diverse cellular processes and homeostasis. Several …

Depression is a clinically common and easily overlooked mental disease. Quercetin is a
flavonoid compound, which has anti-inflammatory and antioxidant roles. Previous reports …

Nociceptors are receptors specifically involved in detecting a tissue damage and
transducing it in an electrical signal. Nociceptor activation provoked by any kind of acute …

Key points The real impact of physical exercise parameters, ie intensity, type of contraction
and solicited energetic metabolism, on neuroprotection in the specific context of …

Peripheral nerve injuries, including motor neuron axonal injury, often lead to functional
impairments. Current therapies are mostly limited to surgical intervention after lesion, yet …

Abstract Apolipoprotein E4 (ApoE4), the most prevalent genetic risk factor for Alzheimer's
disease (AD), is associated with increased neurodegeneration and vascular impairments …

The peripheral nervous system has an intrinsic ability to regenerate after injury. However,
this process is slow, incomplete, and often accompanied by disturbing motor and sensory …

Research into stroke is driven by frustration over the limited available therapeutics.
Targeting a single aspect of this multifactorial disease contributes to the therapeutic …

Objective: To investigate the effects and mechanisms of microRNA 206 (miRNA-206) on
neurological recovery through Notch receptor 3 (Notch3). Methods: The sciatic functional …