Intravenous immunoglobulin (IVIG) preparations comprise pooled IgG antibodies from the
serum of thousands of donors and were initially used as an IgG replacement therapy in …

Intravenous Immune Globulin in Autoimmune and Inflammatory Diseases | New England Journal
of Medicine Skip to main content The New England Journal of Medicine homepage Advanced …

The rapid elimination of nanoparticles from the bloodstream by the mononuclear phagocyte
system limits the activity of many nanoparticle formulations. Here, we show that inducing a …

B cells are typically characterized by their ability to produce Abs, including autoantibodies.
However, B cells possess additional immune functions, including the production of cytokines …

The remarkable success story of the therapeutic application of pooled immunoglobulin G
(IgG) preparations from thousands of donors, the so-called intravenous IgG (IVIG) therapy, to …

For many years, programmed cell death, known as apoptosis, was attributed exclusively to
nucleated cells. Currently, however, apoptosis is also well-documented in anucleate …

Numerous mechanisms of action have been proposed for intravenous Ig (IVIG). In this study,
we used IgG passive transfer murine models of bullous pemphigoid (BP), pemphigus …

Despite a more than 20-year experience of therapeutic benefit, the relevant molecular and
cellular targets of intravenous immunoglobulin (IVIg) in autoimmune disease remain …

Haematological complications are frequently seen in SLE. Anaemia, leucopenias and
thrombocytopenia may result from bone marrow failure or excessive peripheral cell …

Intravenous immunoglobulin (IVIg) is therapeutically used in a variety of immune-mediated
diseases. The beneficial effects of IVIg in auto-antibody-mediated diseases can be …