Cell–extracellular matrix mechanotransduction in 3D

A Saraswathibhatla, D Indana… - Nature Reviews Molecular …, 2023 - nature.com
Mechanical properties of extracellular matrices (ECMs) regulate essential cell behaviours,
including differentiation, migration and proliferation, through mechanotransduction. Studies …

[HTML][HTML] 3D printing of hydrogels: Rational design strategies and emerging biomedical applications

J Li, C Wu, PK Chu, M Gelinsky - Materials Science and Engineering: R …, 2020 - Elsevier
Abstract 3D printing alias additive manufacturing can transform 3D virtual models created by
computer-aided design (CAD) into physical 3D objects in a layer-by-layer manner …

Three-dimensional scaffolds for tissue engineering applications: role of porosity and pore size

QL Loh, C Choong - 2013 - liebertpub.com
Tissue engineering applications commonly encompass the use of three-dimensional (3D)
scaffolds to provide a suitable microenvironment for the incorporation of cells or growth …

Structurally dynamic hydrogels for biomedical applications: pursuing a fine balance between macroscopic stability and microscopic dynamics

K Zhang, Q Feng, Z Fang, L Gu, L Bian - Chemical Reviews, 2021 - ACS Publications
Owing to their unique chemical and physical properties, hydrogels are attracting increasing
attention in both basic and translational biomedical studies. Although the classical hydrogels …

Engineered hydrogels for mechanobiology

U Blache, EM Ford, B Ha, L Rijns… - Nature Reviews …, 2022 - nature.com
Cells' local mechanical environment can be as important in guiding cellular responses as
many well-characterized biochemical cues. Hydrogels that mimic the native extracellular …

Advancing biomaterials of human origin for tissue engineering

FM Chen, X Liu - Progress in polymer science, 2016 - Elsevier
Biomaterials have played an increasingly prominent role in the success of biomedical
devices and in the development of tissue engineering, which seeks to unlock the …

Functional and biomimetic materials for engineering of the three-dimensional cell microenvironment

G Huang, F Li, X Zhao, Y Ma, Y Li, M Lin, G **… - Chemical …, 2017 - ACS Publications
The cell microenvironment has emerged as a key determinant of cell behavior and function
in development, physiology, and pathophysiology. The extracellular matrix (ECM) within the …

25th anniversary article: Rational design and applications of hydrogels in regenerative medicine

N Annabi, A Tamayol, JA Uquillas, M Akbari… - Advanced …, 2014 - Wiley Online Library
Hydrogels are hydrophilic polymer‐based materials with high water content and physical
characteristics that resemble the native extracellular matrix. Because of their remarkable …

Mechanical memory and dosing influence stem cell fate

C Yang, MW Tibbitt, L Basta, KS Anseth - Nature materials, 2014 - nature.com
We investigated whether stem cells remember past physical signals and whether these can
be exploited to dose cells mechanically. We found that the activation of the Yes-associated …

Biomedical applications of supramolecular hydrogels with enhanced mechanical properties

J Xu, X Zhu, J Zhao, G Ling, P Zhang - Advances in colloid and interface …, 2023 - Elsevier
Supramolecular hydrogels bound by hydrogen bonding, host-guest, hydrophobic, and other
non-covalent interactions are among the most attractive biomaterials available …