This review on continuum solvation models has been preceded in Chemical Reviews by
others addressing the same subject. They are due to Tomasi and Persico1 (published in …

The issues of electronic polarizability in molecular dynamics simulations are discussed. We
argue that the charges of ionized groups in proteins, and charges of ions in conventional …

Molecular dynamics simulations of ionic systems require the inclusion of long‐range
electrostatic forces. We propose an expression for the long‐range electrostatic forces based …

Electrostatic correlations play an important role in physics, chemistry and biology. In
plasmas they result in thermodynamic instability similar to the liquid–gas phase transition of …

302 SHARP & HONIG who then jumped in unison to the great amusement of the onlookers
(67a). The point of the story, in the context of the article,. was that" electrostatics was not …

Structural and mutational analyses reveal a central role for electrostatic interactions in
protein–protein association. Experiment and theory both demonstrate that clusters of …

Microsomal NADPH–cytochrome P450 reductase (CPR) is one of only two mammalian
enzymes known to contain both FAD and FMN, the other being nitric-oxide synthase. CPR is …

Because of its unique properties, water drives many natural and biological processes. While
a detailed understanding of its precise role is still being unravelled, it is clear that the …

Background Accurate modeling of electrostatic potential and corresponding energies
becomes increasingly important for understanding properties of biological macromolecules …

Two types of noncovalent bonding interactions are present in protein structures, specific and
nonspecific. Nonspecific interactions are mostly hydrophobic and van der Waals. Specific …