The human microbiome constitutes a complex multikingdom community that symbiotically
interacts with the host across multiple body sites. Host-microbiome interactions impact …

Probiotics have been used to treat a variety of diseases for decades; however, what is the
rationale for their application? Such a treatment was first proposed in the early nineteenth …

Microbes inhabiting the intestinal tract of humans represent a site for xenobiotic metabolism.
The gut microbiome, the collection of microorganisms in the gastrointestinal tract, can alter …

Bacteria present in probiotics, particularly the common Lactobacillus and Bifidobacterium
microbes, have been found to induce anti-cancer action by enhancing cancer cell apoptosis …

Cancer is a major health burden worldwide, and despite continuous advances in medical
therapies, resistance to standard drugs and adverse effects still represent an important …

Motivation Human microbes play critical roles in drug development and precision medicine.
How to systematically understand the complex interaction mechanism between human …

Breast cancer is the most common malignancy in women worldwide. The cause of cancer is
multifactorial. An early diagnosis and the appropriate treatment of cancer can improve the …

Background Successful chemoprevention or chemotherapy is achieved through targeted
delivery of prophylactic agents during initial phases of carcinogenesis or therapeutic agents …

Recently, preclinical and clinical studies targeting several types of cancer strongly supported
the key role of the gut microbiota in the modulation of host response to anti-tumoral …

Colorectal cancer (CRC) is the second leading cause of cancer worldwide. CRC is still
associated with a poor prognosis among patients with advanced disease. On the contrary …