Studies of the retinal microcirculation using human donor eyes and high-resolution clinical imaging: insights gained to guide future research in diabetic retinopathy
The microcirculation plays a key role in delivering oxygen to and removing metabolic wastes
from energy-intensive retinal neurons. Microvascular changes are a hallmark feature of …
from energy-intensive retinal neurons. Microvascular changes are a hallmark feature of …
Towards the Clinical utility of CFD for assessment of intracranial aneurysm rupture–a systematic review and novel parameter-ranking tool
Background Intracranial aneurysms (IAs) are vascular dilations on cerebral vessels that
affect between 1%–5% of the general population, and can cause life-threatening intracranial …
affect between 1%–5% of the general population, and can cause life-threatening intracranial …
Association of wall shear stress with intracranial aneurysm rupture: systematic review and meta-analysis
G Zhou, Y Zhu, Y Yin, M Su, M Li - Scientific reports, 2017 - nature.com
To evaluate the relationship between wall shear stress (WSS) magnitude and cerebral
aneurysm rupture and provide new insight into the disparate computational fluid dynamics …
aneurysm rupture and provide new insight into the disparate computational fluid dynamics …
A comprehensive investigation of morphological features responsible for cerebral aneurysm rupture using machine learning
Cerebral aneurysms are a silent yet prevalent condition that affects a significant global
population. Their development can be attributed to various factors, presentations, and …
population. Their development can be attributed to various factors, presentations, and …
Development and internal validation of an aneurysm rupture probability model based on patient characteristics and aneurysm location, morphology, and …
Purpose Unruptured cerebral aneurysms pose a dilemma for physicians who need to weigh
the risk of a devastating subarachnoid hemorrhage against the risk of surgery or …
the risk of a devastating subarachnoid hemorrhage against the risk of surgery or …
Rupture risk assessment for multiple intracranial aneurysms: why there is no need for dozens of clinical, morphological and hemodynamic parameters
B Neyazi, VM Swiatek, M Skalej… - Therapeutic …, 2020 - journals.sagepub.com
Introduction: A multitude of approaches have been postulated for assessing the risk of
intracranial aneurysm rupture. However, the amount of potential predictive factors is not …
intracranial aneurysm rupture. However, the amount of potential predictive factors is not …
The PHASES score: to treat or not to treat? Retrospective evaluation of the risk of rupture of intracranial aneurysms in patients with aneurysmal subarachnoid …
Background and purpose The PHASES score was formulated to predict the 5-year risk of
rupture for intracranial aneurysms. We retrospectively analyzed all patients treated in our …
rupture for intracranial aneurysms. We retrospectively analyzed all patients treated in our …
Hemodynamic and morphological characteristics of a growing cerebral aneurysm
The growth of cerebral aneurysms is linked to local hemodynamic conditions, but the driving
mechanisms of the growth are poorly understood. The goal of this study was to examine the …
mechanisms of the growth are poorly understood. The goal of this study was to examine the …
Morphological characteristics of ruptured brain aneurysms: a systematic literature review and meta‐analysis
S Sanchez, M Hickerson, RR Patel… - Stroke: Vascular and …, 2023 - Am Heart Assoc
Background It is unclear what morphological features of brain aneurysms are better at
predicting risk of rupture. We conducted a meta‐analysis to analyze the best morphological …
predicting risk of rupture. We conducted a meta‐analysis to analyze the best morphological …
Role of hemodynamic forces in unruptured intracranial aneurysms: an overview of a complex scenario
Background An understanding of the natural history of unruptured intracranial aneurysms
(IAs) has always played a critical role in presurgical or endovascular planning, to avoid …
(IAs) has always played a critical role in presurgical or endovascular planning, to avoid …