Metal-catalyzed regiodivergent organic reactions

C Nájera, IP Beletskaya, M Yus - Chemical Society Reviews, 2019‏ - pubs.rsc.org
Metal-catalyzed regiodivergent reactions allow control over regioselectivity in the synthesis
of a wide range of organic products. Starting from the same material, it is possible to prepare …

The unique fluorine effects in organic reactions: recent facts and insights into fluoroalkylations

C Ni, J Hu - Chemical Society Reviews, 2016‏ - pubs.rsc.org
Fluoroalkylation reaction, featuring the transfer of a fluoroalkyl group to a substrate, is a
straightforward and efficient method for the synthesis of organofluorine compounds. In …

Wonderful fusion of organofluorine chemistry and decarboxylation strategy

P **ao, X Pannecoucke, JP Bouillon… - Chemical Society …, 2021‏ - pubs.rsc.org
Decarboxylation strategy has been emerging as a powerful tool for the synthesis of fluorine-
containing organic compounds that play important roles in various fields such as …

Pd/NHC-Controlled Regiodivergent Defluorinative Allylation of gem-Difluorocyclopropanes with Allylboronates

L Lv, H Qian, AB Crowell, S Chen, Z Li - ACS Catalysis, 2022‏ - ACS Publications
Controlling the selectivity of synthetically useful reactions has been a longstanding objective
of organic chemistry. We report a regiodivergent synthetic protocol allowing access to …

Ligand-controlled regioselective and chemodivergent defluorinative functionalization of gem-difluorocyclopropanes with simple ketones

L Lv, H Qian, Y Ma, S Huang, X Yan, Z Li - Chemical Science, 2021‏ - pubs.rsc.org
Modulating the reaction selectivity is highly attractive and pivotal to the rational design of
synthetic regimes. The defluorinative functionalization of gem-difluorocyclopropanes …

Ligand‐Controlled Regiodivergent Copper‐Catalyzed Alkylboration of Alkenes

W Su, TJ Gong, X Lu, MY Xu, CG Yu… - Angewandte Chemie …, 2015‏ - Wiley Online Library
A novel copper‐catalyzed regiodivergent alkylboration of alkenes with bis (pinacolato)
diboron and alkyl halides has been developed. The regioselectivity of the alkylboration was …

Advances in transition-metal-mediated di-and monofluoroalkylations

C Ni, L Zhu, J Hu - Acta Chimica Sinica, 2015‏ - sioc-journal.cn
Transition-metal-mediated fluoroalkylation is a hot research topic in current organofluorine
chemistry. In the past five years, due to the development of new perfluoroalkylation reagents …

Asymmetric γ‐allylation of α, β‐unsaturated aldehydes by combined organocatalysis and transition‐metal catalysis

L Næsborg, KS Halskov, F Tur… - Angewandte …, 2015‏ - Wiley Online Library
The first asymmetric regio‐and diastereodivergent γ‐allylation of cyclic α, β‐unsaturated
aldehydes based on combined organocatalysis and transition‐metal catalysis is disclosed …

Ligand‐and Solvent‐Controlled Regio‐and Chemodivergent Carbonylative Reactions

JB Peng, XF Wu - Angewandte Chemie International Edition, 2018‏ - Wiley Online Library
The development of highly selective procedures is one of the core goals in organic
chemistry. Among the known organic transformations, carbonylation reactions present an …

Copper-Catalyzed C–H Difluoroalkylations and Perfluoroalkylations of Alkenes and (Hetero) arenes

X Wang, S Zhao, J Liu, D Zhu, M Guo, X Tang… - Organic …, 2017‏ - ACS Publications
A general and facile synthetic method for C (sp2)–H difluoroalkylations and
perfluoroalkylations of alkenes and (hetero) arenes with commercially available fluoroalkyl …