The TGF-β regulatory system plays crucial roles in the preservation of organismal integrity.
TGF-β signaling controls metazoan embryo development, tissue homeostasis, and injury …

Transforming growth factor-β (TGFβ) signalling controls multiple cell fate decisions during
development and tissue homeostasis; hence, dysregulation of this pathway can drive …

Idiopathic pulmonary fibrosis (IPF) is an aggressive interstitial lung disease with a high
mortality rate. Putative drug targets in IPF have failed to translate into effective therapies at …

The molecular pathology of multi-organ injuries in COVID-19 patients remains unclear,
preventing effective therapeutics development. Here, we report a proteomic analysis of 144 …

Traditional wound dressings mainly participate in the passive healing processes and are
rarely engaged in active wound healing by stimulating skin cell behaviors. Electrical …

Effective healing of skin wounds is essential for our survival. Although skin has strong
regenerative potential, dysfunctional and disfiguring scars can result from aberrant wound …

The native tissues are complex structures consisting of different cell types, extracellular
matrix materials, and biomolecules. Traditional tissue engineering strategies have not been …

Numerous studies have demonstrated that endothelial cells are capable of undergoing
endothelial to mesenchymal transition (EndMT), a newly recognized type of cellular …

Mast cells are hematopoietic cells that reside in virtually all vascularized tissues and that
represent potential sources of a wide variety of biologically active secreted products …

Renal tubules are the major component of the kidney and are vulnerable to a variety of
injuries including hypoxia, proteinuria, toxins, metabolic disorders, and senescence. It has …