Inflammatory bowel diseases (IBDs) are multifactorial autoimmune diseases with growing
prevalence but the interaction between genetic, environmental and immunologic factors in …

The link between the gut and the brain in Parkinson's disease (PD) pathogenesis is currently
a subject of intense research. Indeed, gastrointestinal dysfunction is known as an early …

Leucine-rich repeat kinase 2 (LRRK2) is a common gene implicated in Parkinson's disease
and many inflammatory processes. Thus, we assessed the role of LRRK2 in the context of …

Background The leucine‐rich repeat kinase 2 (LRRK2) gene harbors both rare highly
damaging missense variants (eg, p. G2019S) and common noncoding variants (eg …

Background: Involvement of gastrointestinal inflammation in Parkinson's disease (PD)
pathogenesis and movement have progressively emerged. Inflammation is involved in the …

Parkinson's disease (PD) is the most common neurodegenerative motor disease, affecting
10 million people worldwide. To date, PD cannot be cured, instead therapy is directed at …

Bone remodeling disorders including osteoporosis are prevalent worldwide and impact on
quality of life. Better molecular understanding of bone resorbing cells called osteoclasts, can …

Parkinson's disease (PD) is a neurodegenerative disorder characterised by the loss of
dopaminergic neurons in the substantia nigra. Ageing is the major risk factor for develo** …

Background The leucine-rich repeat kinase 2 (LRRK2) gene harbors both rare highly
damaging missense variants (egp G2019S) and common non-coding variants (eg …

Microbiota's influence on human health and disease is a growing research field including
neurodegenerative diseases such as Parkinson's disease (PD). The disease symptoms …