Neutrophils act as the body's first line of defense against infection and respond to diverse
inflammatory cues, including cancer. Neutrophils display plasticity, with the ability to adapt …

Neutrophils are the most abundant of all white blood cells in the human circulation and are
usually associated with inflammation and with fighting infections. In recent years the role …

Tumor-associated and tumor-infiltrating neutrophils (TAN) and macrophages (TAM) can
account for as much as 50% of the total tumor mass in invasive breast carcinomas. It is …

Oncostatin M is a secreted cytokine involved in homeostasis and in diseases involving
chronic inflammation. It is a member of the gp130 family of cytokines that have pleiotropic …

Stromal cells are a subject of rapidly growing immunological interest based on their ability to
influence virtually all aspects of innate and adaptive immunity. Present in every bodily tissue …

Ischemic stroke is one of the main issues threatening human health worldwide, and it is also
the main cause of permanent disability in adults. Energy consumption and hypoxia after …

Oncostatin M (OSM), as a member of the Interleukin-6 family cytokines, plays a significant
role in inflammation, autoimmunity, and cancers. It is mainly secreted by T lymphocytes …

NETs are chromatin-derived webs extruded from neutrophils as a result of either infection or
sterile stimulation using chemicals, cytokines, or microbes. In addition to the classical role …

The progression of breast cancer and its association with clinical outcome and treatment
remain largely unexplored. Accumulating data has highlighted the interaction between cells …

Neutrophils are the key cells of our innate immune system mediating host defense via a
range of effector functions including phagocytosis, degranulation, and NETosis. For this …