Ovarian cancer is an aggressive disease that is frequently detected at advanced stages and
is initially very responsive to platinum-based chemotherapy. However, the majority of …

Breast cancer is the most frequently diagnosed cancer in women, with estrogen receptor
positive (ER+) breast cancer making up approximately 75% of all breast cancers diagnosed …

Fewer than half of all patients with advanced-stage high-grade serous ovarian cancers
(HGSCs) survive more than five years after diagnosis, but those who have an exceptionally …

Importance Cytotoxic CD8+ tumor-infiltrating lymphocytes (TILs) participate in immune
control of epithelial ovarian cancer; however, little is known about prognostic patterns of …

Fitness of cells is dependent on protein homeostasis which is maintained by cooperative
activities of protein chaperones and proteolytic machinery. Upon encountering protein …

Simple Summary Historically, cancers presenting with their main tumor mass in the ovary
have been classified as ovarian carcinomas (a concise term for epithelial ovarian cancer) …

Ovarian carcinoma (OC) is an umbrella term for multiple distinct diseases (histotypes), each
with their own developmental origins, clinical behaviour and molecular profile. Accordingly …

Purpose The purpose of this study was to examine outcomes associated with hormonal
maintenance therapy (HMT) compared with routine observation (OBS) after primary …

In January 2019, a group of basic, translational, and clinical investigators and patient
advocates assembled in Miami, Florida, to discuss the current state of the science of low …

There are 5 major histotypes of ovarian carcinomas. Diagnostic ty** criteria have evolved
over time, and past cohorts may be misclassified by current standards. Our objective was to …